FOXO6 (forkhead box O6)

2016-01-01  

Identity

HGNC
FOXO6
LOCATION
1p34.2
LOCUSID
100132074
ALIAS
-

Other Information

Locus ID:

NCBI: 100132074
MIM: 611457
HGNC: 24814

Variants:

dbSNP: 100132074
ClinVar: 100132074
COSMIC: FOXO6

Expression (GTEx)

0
5
10
15
20
25
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
FoxO signaling pathwayKEGGhsa04068

References

Pubmed IDYearTitleCitations
366884072024FOXO6 transcription inhibition of CTRP3 promotes OGD/R-triggered cardiac microvascular endothelial barrier disruption via SIRT1/Nrf2 signalling.1
366884072024FOXO6 transcription inhibition of CTRP3 promotes OGD/R-triggered cardiac microvascular endothelial barrier disruption via SIRT1/Nrf2 signalling.1
341976552021Association of genetic variants of FBXO32 and FOXO6 in the FOXO pathway with breast cancer risk.0
345076372021LncRNA HOXC-AS1 promotes nasopharyngeal carcinoma (NPC) progression by sponging miR-4651 and subsequently upregulating FOXO6.6
345338132021Upregulation of FoxO6 in nucleus pulposus cells promotes DNA damage repair via activation of RAD51.0
349189622021Knockdown of long non-coding MIR210HG inhibits cell proliferation, migration, and invasion in hepatoblastoma via the microRNA-608-FOXO6 axis.0
341976552021Association of genetic variants of FBXO32 and FOXO6 in the FOXO pathway with breast cancer risk.0
345076372021LncRNA HOXC-AS1 promotes nasopharyngeal carcinoma (NPC) progression by sponging miR-4651 and subsequently upregulating FOXO6.6
345338132021Upregulation of FoxO6 in nucleus pulposus cells promotes DNA damage repair via activation of RAD51.0
349189622021Knockdown of long non-coding MIR210HG inhibits cell proliferation, migration, and invasion in hepatoblastoma via the microRNA-608-FOXO6 axis.0
326396262020Interaction between CHOP and FoxO6 promotes hepatic lipid accumulation.4
331239502020Downregulation of FOXO6 alleviates hypoxia-induced apoptosis and oxidative stress in cardiomyocytes by enhancing Nrf2 activation via upregulation of SIRT6.5
326396262020Interaction between CHOP and FoxO6 promotes hepatic lipid accumulation.4
331239502020Downregulation of FOXO6 alleviates hypoxia-induced apoptosis and oxidative stress in cardiomyocytes by enhancing Nrf2 activation via upregulation of SIRT6.5
303214502019Silencing of FOXO6 inhibits the proliferation, invasion, and glycolysis in colorectal cancer cells.16

Citation

Dessen P

FOXO6 (forkhead box O6)

Atlas Genet Cytogenet Oncol Haematol. 2016-01-01

Online version: http://atlasgeneticsoncology.org/gene/55618/deep-insight-explorer/meetings/welcome