GRHL1 (grainyhead like transcription factor 1)

2015-03-01  

Identity

HGNC
LOCATION
2p25.1
LOCUSID
ALIAS
LBP32,MGR,NH32,TFCP2L2
FUSION GENES

Other Information

Locus ID:

NCBI: 29841
MIM: 609786
HGNC: 17923
Ensembl: ENSG00000134317

Variants:

dbSNP: 29841
ClinVar: 29841
TCGA: ENSG00000134317
COSMIC: GRHL1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000134317ENST00000324907Q9NZI5
ENSG00000134317ENST00000405379Q9NZI5
ENSG00000134317ENST00000439493F8WFB0
ENSG00000134317ENST00000464418B7Z1S6
ENSG00000134317ENST00000472167Q9NZI5
ENSG00000134317ENST00000480736C9JYY8

Expression (GTEx)

0
50
100
150
200

Pathways

PathwaySourceExternal ID
MetabolismREACTOMER-HSA-1430728
Metabolism of lipids and lipoproteinsREACTOMER-HSA-556833
Fatty acid, triacylglycerol, and ketone body metabolismREACTOMER-HSA-535734
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)REACTOMER-HSA-400206
PPARA activates gene expressionREACTOMER-HSA-1989781

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
380497252023Discovery of a non-canonical GRHL1 binding site using deep convolutional and recurrent neural networks.0
380497252023Discovery of a non-canonical GRHL1 binding site using deep convolutional and recurrent neural networks.0
350132372022Grainyhead 1 acts as a drug-inducible conserved transcriptional regulator linked to insulin signaling and lifespan.3
350132372022Grainyhead 1 acts as a drug-inducible conserved transcriptional regulator linked to insulin signaling and lifespan.3
293014992018Coordinated expression and genetic polymorphisms in Grainyhead-like genes in human non-melanoma skin cancers.9
293096422018Structural basis of gene regulation by the Grainyhead/CP2 transcription factor family.19
293014992018Coordinated expression and genetic polymorphisms in Grainyhead-like genes in human non-melanoma skin cancers.9
293096422018Structural basis of gene regulation by the Grainyhead/CP2 transcription factor family.19
287149582017Roles of Grainyhead-like transcription factors in cancer.35
287149582017Roles of Grainyhead-like transcription factors in cancer.35
270355582016Role of estrogen receptor in breast cancer cell gene expression.9
270355582016Role of estrogen receptor in breast cancer cell gene expression.9
258962822015Grhl1 deficiency affects inner ear development in zebrafish.6
260692692015Recent discoveries concerning the involvement of transcription factors from the Grainyhead-like family in cancer.35
258962822015Grhl1 deficiency affects inner ear development in zebrafish.6

Citation

Dessen P

GRHL1 (grainyhead like transcription factor 1)

Atlas Genet Cytogenet Oncol Haematol. 2015-03-01

Online version: http://atlasgeneticsoncology.org/gene/55619/grhl1-(grainyhead-like-transcription-factor-1)