Identity
HGNC
LOCATION
12q24.11
LOCUSID
ALIAS
JBTS13,TECT1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 79600
MIM: 609863
HGNC: 26113
Ensembl: ENSG00000204852
Variants:
dbSNP: 79600
ClinVar: 79600
TCGA: ENSG00000204852
COSMIC: TCTN1
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Organelle biogenesis and maintenance | REACTOME | R-HSA-1852241 |
| Cilium Assembly | REACTOME | R-HSA-5617833 |
| Anchoring of the basal body to the plasma membrane | REACTOME | R-HSA-5620912 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 32486612 | 2023 | microRNA-216a-5p inhibits the development of gastric cancer through target combination with TCTN1. | 2 |
| 32486612 | 2023 | microRNA-216a-5p inhibits the development of gastric cancer through target combination with TCTN1. | 2 |
| 34859261 | 2022 | Function and transcriptional regulation of TCTN1 in oral squamous cell carcinoma. | 2 |
| 34859261 | 2022 | Function and transcriptional regulation of TCTN1 in oral squamous cell carcinoma. | 2 |
| 31302911 | 2019 | [Diagnosis of two cases from one family with Joubert syndrome caused by novel mutations of TCTN1 gene by whole exome sequencing]. | 0 |
| 31302911 | 2019 | [Diagnosis of two cases from one family with Joubert syndrome caused by novel mutations of TCTN1 gene by whole exome sequencing]. | 0 |
| 28123172 | 2017 | Knockdown of TCTN1 Strongly Decreases Growth of Human Colon Cancer Cells. | 8 |
| 28631893 | 2017 | Expanding the allelic disorders linked to TCTN1 to include Varadi syndrome (Orofaciodigital syndrome type VI). | 3 |
| 28123172 | 2017 | Knockdown of TCTN1 Strongly Decreases Growth of Human Colon Cancer Cells. | 8 |
| 28631893 | 2017 | Expanding the allelic disorders linked to TCTN1 to include Varadi syndrome (Orofaciodigital syndrome type VI). | 3 |
| 25737023 | 2015 | Lentivirus-Mediated Knockdown of TCTN1 Inhibits Glioma Cell Proliferation. | 6 |
| 26310786 | 2015 | Tectonic‑1 contributes to the growth and migration of prostate cancer cells in vitro. | 7 |
| 25737023 | 2015 | Lentivirus-Mediated Knockdown of TCTN1 Inhibits Glioma Cell Proliferation. | 6 |
| 26310786 | 2015 | Tectonic‑1 contributes to the growth and migration of prostate cancer cells in vitro. | 7 |
| 25304031 | 2014 | Expression and prognostic significance of TCTN1 in human glioblastoma. | 6 |
Citation
Dessen P
TCTN1 (tectonic family member 1)
Atlas Genet Cytogenet Oncol Haematol. 2015-03-01
Online version: http://atlasgeneticsoncology.org/gene/55624/tctn1-(tectonic-family-member-1)
