Identity
HGNC
LOCATION
19q13.32
LOCUSID
ALIAS
CD112,HVEB,PRR2,PVRL2,PVRR2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 5819
MIM: 600798
HGNC: 9707
Ensembl: ENSG00000130202
Variants:
dbSNP: 5819
ClinVar: 5819
TCGA: ENSG00000130202
COSMIC: NECTIN2
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38408961 | 2024 | The SNP rs6859 in NECTIN2 gene is associated with underlying heterogeneous trajectories of cognitive changes in older adults. | 1 |
| 38474388 | 2024 | CD112 Supports Lymphatic Migration of Human Dermal Dendritic Cells. | 0 |
| 38588410 | 2024 | PVRL2 Suppresses Antitumor Immunity through PVRIG- and TIGIT-independent Pathways. | 0 |
| 38592213 | 2024 | Exercise-induced β2-adrenergic Receptor Activation Enhances the Antileukemic Activity of Expanded γδ T-Cells via DNAM-1 Upregulation and PVR/Nectin-2 Recognition. | 0 |
| 38408961 | 2024 | The SNP rs6859 in NECTIN2 gene is associated with underlying heterogeneous trajectories of cognitive changes in older adults. | 1 |
| 38474388 | 2024 | CD112 Supports Lymphatic Migration of Human Dermal Dendritic Cells. | 0 |
| 38588410 | 2024 | PVRL2 Suppresses Antitumor Immunity through PVRIG- and TIGIT-independent Pathways. | 0 |
| 38592213 | 2024 | Exercise-induced β2-adrenergic Receptor Activation Enhances the Antileukemic Activity of Expanded γδ T-Cells via DNAM-1 Upregulation and PVR/Nectin-2 Recognition. | 0 |
| 36916296 | 2023 | Nectin2 influences cell apoptosis by regulating ANXA2 expression in neuroblastoma. | 2 |
| 37108578 | 2023 | Metabolic Overlap between Alzheimer's Disease and Metabolic Syndrome Identifies the PVRL2 Gene as a New Modulator of Diabetic Dyslipidemia. | 2 |
| 37378949 | 2023 | Relative Expression of BATF and CD112 in PBMC of Patients with Chronic Lymphocytic Leukemia. | 0 |
| 37383234 | 2023 | Single-cell RNA sequencing highlights the role of PVR/PVRL2 in the immunosuppressive tumour microenvironment in hepatocellular carcinoma. | 2 |
| 36916296 | 2023 | Nectin2 influences cell apoptosis by regulating ANXA2 expression in neuroblastoma. | 2 |
| 37108578 | 2023 | Metabolic Overlap between Alzheimer's Disease and Metabolic Syndrome Identifies the PVRL2 Gene as a New Modulator of Diabetic Dyslipidemia. | 2 |
| 37378949 | 2023 | Relative Expression of BATF and CD112 in PBMC of Patients with Chronic Lymphocytic Leukemia. | 0 |
Citation
Dessen P
NECTIN2 (nectin cell adhesion molecule 2)
Atlas Genet Cytogenet Oncol Haematol. 2015-03-01
Online version: http://atlasgeneticsoncology.org/gene/55629/nectin2-(nectin-cell-adhesion-molecule-2)
