Identity
HGNC
LOCATION
22q13.2
LOCUSID
ALIAS
GRAMD7,PAWP
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 164684
MIM: 610981
HGNC: 28389
Ensembl: ENSG00000183066
Variants:
dbSNP: 164684
ClinVar: 164684
TCGA: ENSG00000183066
COSMIC: WBP2NL
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 28954204 | 2018 | Oligoasthenoteratozoospermic (OAT) men display altered phospholipase C ζ (PLCζ) localization and a lower percentage of sperm cells expressing PLCζ and post-acrosomal sheath WW domain-binding protein (PAWP). | 8 |
| 29271520 | 2018 | Is there an association between PAWP/WBP2NL sequence, expression, and distribution in sperm cells and fertilization failures in ICSI cycles? | 0 |
| 28954204 | 2018 | Oligoasthenoteratozoospermic (OAT) men display altered phospholipase C ζ (PLCζ) localization and a lower percentage of sperm cells expressing PLCζ and post-acrosomal sheath WW domain-binding protein (PAWP). | 8 |
| 29271520 | 2018 | Is there an association between PAWP/WBP2NL sequence, expression, and distribution in sperm cells and fertilization failures in ICSI cycles? | 0 |
| 28076980 | 2017 | Status of sperm-born oocyte activating factors (PAWP, PLCζ) and sperm chromatin in uncapacitated, capacitated and acrosome-reacted conditions. | 1 |
| 28444612 | 2017 | WBP2NL/PAWP mRNA and protein expression in sperm cells are not related to semen parameters, fertilization rate, or reproductive outcome. | 6 |
| 28076980 | 2017 | Status of sperm-born oocyte activating factors (PAWP, PLCζ) and sperm chromatin in uncapacitated, capacitated and acrosome-reacted conditions. | 1 |
| 28444612 | 2017 | WBP2NL/PAWP mRNA and protein expression in sperm cells are not related to semen parameters, fertilization rate, or reproductive outcome. | 6 |
| 26721930 | 2016 | Homozygous mutation of PLCZ1 leads to defective human oocyte activation and infertility that is not rescued by the WW-binding protein PAWP. | 60 |
| 27089467 | 2016 | Expression profile of PLCζ, PAWP, and TR-KIT in association with fertilization potential, embryo development, and pregnancy outcomes in globozoospermic candidates for intra-cytoplasmic sperm injection and artificial oocyte activation. | 19 |
| 26721930 | 2016 | Homozygous mutation of PLCZ1 leads to defective human oocyte activation and infertility that is not rescued by the WW-binding protein PAWP. | 60 |
| 27089467 | 2016 | Expression profile of PLCζ, PAWP, and TR-KIT in association with fertilization potential, embryo development, and pregnancy outcomes in globozoospermic candidates for intra-cytoplasmic sperm injection and artificial oocyte activation. | 19 |
| 25417742 | 2015 | The Evaluation of WBP2NL-Related Genes Expression in Breast Cancer. | 10 |
| 25722320 | 2015 | PLCζ or PAWP: revisiting the putative mammalian sperm factor that triggers egg activation and embryogenesis. | 19 |
| 26116451 | 2015 | Functional disparity between human PAWP and PLCζ in the generation of Ca2+ oscillations for oocyte activation. | 14 |
Citation
Dessen P
WBP2NL (WBP2 N-terminal like)
Atlas Genet Cytogenet Oncol Haematol. 2015-03-01
Online version: http://atlasgeneticsoncology.org/gene/55633/wbp2nl-(wbp2-n-terminal-like)
