Identity
HGNC
LOCATION
6q24.2
LOCUSID
ALIAS
FHL4,HLH4,HPLH4
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 8676
MIM: 605014
HGNC: 11429
Ensembl: ENSG00000135604
Variants:
dbSNP: 8676
ClinVar: 8676
TCGA: ENSG00000135604
COSMIC: STX11
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000135604 | ENST00000367568 | O75558 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| SNARE interactions in vesicular transport | KEGG | ko04130 |
| SNARE interactions in vesicular transport | KEGG | hsa04130 |
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA166182763 | emapalumab | Chemical | LabelAnnotation | associated |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38198890 | 2024 | Dynamic palmitoylation of STX11 controls injury-induced fatty acid uptake to promote muscle regeneration. | 0 |
| 38722309 | 2024 | Patients and mice with deficiency in the SNARE protein SYNTAXIN-11 have a secondary B cell defect. | 0 |
| 38198890 | 2024 | Dynamic palmitoylation of STX11 controls injury-induced fatty acid uptake to promote muscle regeneration. | 0 |
| 38722309 | 2024 | Patients and mice with deficiency in the SNARE protein SYNTAXIN-11 have a secondary B cell defect. | 0 |
| 36728431 | 2023 | Syntaxin 11 Contributes to the Interferon-Inducible Restriction of Coxiella burnetii Intracellular Infection. | 1 |
| 36728431 | 2023 | Syntaxin 11 Contributes to the Interferon-Inducible Restriction of Coxiella burnetii Intracellular Infection. | 1 |
| 35293882 | 2022 | Familial Hemophagocytic Lymphohistiocytosis With Heterozygous STX11 and Homozygous UNC13D Mutations Diagnosed in the Neonatal Period. | 0 |
| 35293882 | 2022 | Familial Hemophagocytic Lymphohistiocytosis With Heterozygous STX11 and Homozygous UNC13D Mutations Diagnosed in the Neonatal Period. | 0 |
| 34339548 | 2021 | Spectrum mutations of PRF1, UNC13D, STX11, and STXBP2 genes in Vietnamese patients with hemophagocytic lymphohistiocytosis. | 3 |
| 34339548 | 2021 | Spectrum mutations of PRF1, UNC13D, STX11, and STXBP2 genes in Vietnamese patients with hemophagocytic lymphohistiocytosis. | 3 |
| 31207086 | 2019 | STX11-deficient familial hemophagocytic lymphohistiocytosis type 4 is associated with self-resolving flares and a milder clinical course. | 0 |
| 31207086 | 2019 | STX11-deficient familial hemophagocytic lymphohistiocytosis type 4 is associated with self-resolving flares and a milder clinical course. | 0 |
| 29352103 | 2018 | Dynamic cycling of t-SNARE acylation regulates platelet exocytosis. | 4 |
| 29352103 | 2018 | Dynamic cycling of t-SNARE acylation regulates platelet exocytosis. | 4 |
| 29044293 | 2017 | Down Regulation of the Munc18b-syntaxin-11 Complex and β1-tubulin Impairs Secretion and Spreading in Neonatal Platelets. | 16 |
Citation
Dessen P
STX11 (syntaxin 11)
Atlas Genet Cytogenet Oncol Haematol. 2015-03-01
Online version: http://atlasgeneticsoncology.org/gene/55638/stx11-(syntaxin-11)
