CPEB2 (cytoplasmic polyadenylation element binding protein 2)

2015-03-01  

Identity

HGNC
LOCATION
4p15.32
LOCUSID
ALIAS
CPE-BP2,CPEB-2,hCPEB-2
FUSION GENES

Other Information

Locus ID:

NCBI: 132864
MIM: 610605
HGNC: 21745
Ensembl: ENSG00000137449

Variants:

dbSNP: 132864
ClinVar: 132864
TCGA: ENSG00000137449
COSMIC: CPEB2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000137449ENST00000345451Q7Z5Q1
ENSG00000137449ENST00000382395Q7Z5Q1
ENSG00000137449ENST00000382401Q7Z5Q1
ENSG00000137449ENST00000442003Q7Z5Q1
ENSG00000137449ENST00000507071Q7Z5Q1
ENSG00000137449ENST00000509684H0Y9D9
ENSG00000137449ENST00000538197Q7Z5Q1

Expression (GTEx)

0
5
10
15
20
25
30
35

Pathways

PathwaySourceExternal ID
Dorso-ventral axis formationKEGGko04320
Progesterone-mediated oocyte maturationKEGGko04914
Dorso-ventral axis formationKEGGhsa04320
Progesterone-mediated oocyte maturationKEGGhsa04914
Oocyte meiosisKEGGko04114
Oocyte meiosisKEGGhsa04114

References

Pubmed IDYearTitleCitations
372315212023CPEB2 enhances cell growth and angiogenesis by upregulating ARPC5 mRNA stability in multiple myeloma.1
381584312023CPEB2 inhibit cell proliferation through upregulating p21 mRNA stability in glioma.0
372315212023CPEB2 enhances cell growth and angiogenesis by upregulating ARPC5 mRNA stability in multiple myeloma.1
381584312023CPEB2 inhibit cell proliferation through upregulating p21 mRNA stability in glioma.0
360647472022CPEB2 m6A methylation regulates blood-tumor barrier permeability by regulating splicing factor SRSF5 stability.14
360647472022CPEB2 m6A methylation regulates blood-tumor barrier permeability by regulating splicing factor SRSF5 stability.14
316169342020A positive feedback self-regulatory loop between miR-210 and HIF-1α mediated by CPEB2 is involved in trophoblast syncytialization: implication of trophoblast malfunction in preeclampsia†.9
324405352020The RNA binding protein CPEB2 regulates hormone sensing in mammary gland development and luminal breast cancer.9
316169342020A positive feedback self-regulatory loop between miR-210 and HIF-1α mediated by CPEB2 is involved in trophoblast syncytialization: implication of trophoblast malfunction in preeclampsia†.9
324405352020The RNA binding protein CPEB2 regulates hormone sensing in mammary gland development and luminal breast cancer.9
311386012019Serine/Arginine-Rich Splicing Factor 3 Modulates the Alternative Splicing of Cytoplasmic Polyadenylation Element Binding Protein 2.4
311859862019Tumor suppressor role of cytoplasmic polyadenylation element binding protein 2 (CPEB2) in human mammary epithelial cells.12
311386012019Serine/Arginine-Rich Splicing Factor 3 Modulates the Alternative Splicing of Cytoplasmic Polyadenylation Element Binding Protein 2.4
311859862019Tumor suppressor role of cytoplasmic polyadenylation element binding protein 2 (CPEB2) in human mammary epithelial cells.12
283024872017TUG1 mediates methotrexate resistance in colorectal cancer via miR-186/CPEB2 axis.43

Citation

Dessen P

CPEB2 (cytoplasmic polyadenylation element binding protein 2)

Atlas Genet Cytogenet Oncol Haematol. 2015-03-01

Online version: http://atlasgeneticsoncology.org/gene/55640/cpeb2-(cytoplasmic-polyadenylation-element-binding-protein-2)