MELTF (melanotransferrin)

2015-03-01  

Identity

HGNC
MELTF
LOCATION
3q29
LOCUSID
4241
ALIAS
CD228,MAP97,MFI2,MTF1,MTf
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 4241
MIM: 155750
HGNC: 7037
Ensembl: ENSG00000163975

Variants:

dbSNP: 4241
ClinVar: 4241
TCGA: ENSG00000163975
COSMIC: MELTF

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000163975ENST00000296350P08582
ENSG00000163975ENST00000296351P08582
ENSG00000163975ENST00000296351Q53XS6
ENSG00000163975ENST00000439320C9JVN1

Expression (GTEx)

0
5
10
15
20
25
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Metabolism of proteinsREACTOMER-HSA-392499
Post-translational protein modificationREACTOMER-HSA-597592
Post-translational modification: synthesis of GPI-anchored proteinsREACTOMER-HSA-163125

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
383266452024Characterizing ATP processing by the AAA+ protein p97 at the atomic level.1
383266452024Characterizing ATP processing by the AAA+ protein p97 at the atomic level.1
363030862023MELTF Might Regulate Ferroptosis, Pyroptosis, and Autophagy in Platelet-Rich Plasma-Mediated Endometrial Epithelium Regeneration.4
378205702023The E2F1/MELTF axis fosters the progression of lung adenocarcinoma by regulating the Notch signaling pathway.0
363030862023MELTF Might Regulate Ferroptosis, Pyroptosis, and Autophagy in Platelet-Rich Plasma-Mediated Endometrial Epithelium Regeneration.4
378205702023The E2F1/MELTF axis fosters the progression of lung adenocarcinoma by regulating the Notch signaling pathway.0
337465742021The Role of Melanotransferrin (CD228) in the regulation of the differentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells (hBM-MSC).3
339315862021The hypoxia sensitive metal transcription factor MTF-1 activates NCX1 brain promoter and participates in remote postconditioning neuroprotection in stroke.8
337465742021The Role of Melanotransferrin (CD228) in the regulation of the differentiation of Human Bone Marrow-Derived Mesenchymal Stem Cells (hBM-MSC).3
339315862021The hypoxia sensitive metal transcription factor MTF-1 activates NCX1 brain promoter and participates in remote postconditioning neuroprotection in stroke.8
317048402019Level of Melanotransferrin in Tissue and Sera Serves as a Prognostic Marker of Gastric Cancer.10
317048402019Level of Melanotransferrin in Tissue and Sera Serves as a Prognostic Marker of Gastric Cancer.10
252163272014Discovery of melanotransferrin as a serological marker of colorectal cancer by secretome analysis and quantitative proteomics.18
252163272014Discovery of melanotransferrin as a serological marker of colorectal cancer by secretome analysis and quantitative proteomics.18
211905622010PC3 prostate tumor-initiating cells with molecular profile FAM65Bhigh/MFI2low/LEF1low increase tumor angiogenesis.21

Citation

Dessen P

MELTF (melanotransferrin)

Atlas Genet Cytogenet Oncol Haematol. 2015-03-01

Online version: http://atlasgeneticsoncology.org/gene/55648/meltf-(melanotransferrin)