Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 730249
MIM: 615275
HGNC: 33904
Ensembl: ENSG00000102794
Variants:
dbSNP: 730249
ClinVar: 730249
TCGA: ENSG00000102794
COSMIC: ACOD1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000102794 | ENST00000377462 | A6NK06 |
| ENSG00000102794 | ENST00000449753 | H7C1Q4 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38520689 | 2024 | Acod1 expression in cancer cells promotes immune evasion through the generation of inhibitory peptides. | 0 |
| 38520689 | 2024 | Acod1 expression in cancer cells promotes immune evasion through the generation of inhibitory peptides. | 0 |
| 36479617 | 2023 | Macrophages inhibit Coxiella burnetii by the ACOD1-itaconate pathway for containment of Q fever. | 9 |
| 37096266 | 2023 | [Clinical features of 6 children with uridine-responsive developmental epileptic encephalopathy 50 caused by CAD gene variants]. | 0 |
| 37115931 | 2023 | Targeting IRG1 reverses the immunosuppressive function of tumor-associated macrophages and enhances cancer immunotherapy. | 17 |
| 37365251 | 2023 | Amino acid positions near the active site determine the reduced activity of human ACOD1 compared to murine ACOD1. | 2 |
| 36479617 | 2023 | Macrophages inhibit Coxiella burnetii by the ACOD1-itaconate pathway for containment of Q fever. | 9 |
| 37096266 | 2023 | [Clinical features of 6 children with uridine-responsive developmental epileptic encephalopathy 50 caused by CAD gene variants]. | 0 |
| 37115931 | 2023 | Targeting IRG1 reverses the immunosuppressive function of tumor-associated macrophages and enhances cancer immunotherapy. | 17 |
| 37365251 | 2023 | Amino acid positions near the active site determine the reduced activity of human ACOD1 compared to murine ACOD1. | 2 |
| 36001682 | 2022 | Aconitate decarboxylase 1 is a mediator of polymicrobial sepsis. | 13 |
| 36001682 | 2022 | Aconitate decarboxylase 1 is a mediator of polymicrobial sepsis. | 13 |
| 34607464 | 2021 | The Tumor Necrosis Factor Alpha and Interleukin 6 Auto-paracrine Signaling Loop Controls Mycobacterium avium Infection via Induction of IRF1/IRG1 in Human Primary Macrophages. | 12 |
| 34607464 | 2021 | The Tumor Necrosis Factor Alpha and Interleukin 6 Auto-paracrine Signaling Loop Controls Mycobacterium avium Infection via Induction of IRF1/IRG1 in Human Primary Macrophages. | 12 |
| 31997373 | 2020 | Immune-Responsive Gene 1/Itaconate Activates Nuclear Factor Erythroid 2-Related Factor 2 in Hepatocytes to Protect Against Liver Ischemia-Reperfusion Injury. | 85 |
Citation
Dessen P
ACOD1 (aconitate decarboxylase 1)
Atlas Genet Cytogenet Oncol Haematol. 2016-03-01
Online version: http://atlasgeneticsoncology.org/gene/55679/acod1-(aconitate-decarboxylase-1)
