Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 51185
MIM: 609262
HGNC: 30185
Ensembl: ENSG00000113851
Variants:
dbSNP: 51185
ClinVar: 51185
TCGA: ENSG00000113851
COSMIC: CRBN
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38163319 | 2024 | Thrombospondin-1 is an endogenous substrate of cereblon responsible for immunomodulatory drug-induced thromboembolism. | 0 |
| 38163319 | 2024 | Thrombospondin-1 is an endogenous substrate of cereblon responsible for immunomodulatory drug-induced thromboembolism. | 0 |
| 37458657 | 2023 | Incidence of cereblon protein in intensive care patients: a cross-sectional study. | 1 |
| 37458657 | 2023 | Incidence of cereblon protein in intensive care patients: a cross-sectional study. | 1 |
| 35013300 | 2022 | A proximity biotinylation-based approach to identify protein-E3 ligase interactions induced by PROTACs and molecular glues. | 15 |
| 36164994 | 2022 | CRBN is downregulated in lung cancer and negatively regulates TLR2, 4 and 7 stimulation in lung cancer cells. | 4 |
| 36261529 | 2022 | The E3 ligase adapter cereblon targets the C-terminal cyclic imide degron. | 21 |
| 35013300 | 2022 | A proximity biotinylation-based approach to identify protein-E3 ligase interactions induced by PROTACs and molecular glues. | 15 |
| 36164994 | 2022 | CRBN is downregulated in lung cancer and negatively regulates TLR2, 4 and 7 stimulation in lung cancer cells. | 4 |
| 36261529 | 2022 | The E3 ligase adapter cereblon targets the C-terminal cyclic imide degron. | 21 |
| 33443552 | 2021 | Multiple cereblon genetic changes are associated with acquired resistance to lenalidomide or pomalidomide in multiple myeloma. | 63 |
| 33830389 | 2021 | Circ_0114428 Regulates Sepsis-Induced Kidney Injury by Targeting the miR-495-3p/CRBN Axis. | 13 |
| 33972400 | 2021 | Cereblon Regulates the Proteotoxicity of Tau by Tuning the Chaperone Activity of DNAJA1. | 3 |
| 34115836 | 2021 | Cereblon enhancer methylation and IMiD resistance in multiple myeloma. | 21 |
| 34373585 | 2021 | Mutations in CRBN and other cereblon pathway genes are infrequently associated with acquired resistance to immunomodulatory drugs. | 6 |
Citation
Dessen P
CRBN (cereblon)
Atlas Genet Cytogenet Oncol Haematol. 2016-03-01
Online version: http://atlasgeneticsoncology.org/gene/55691/crbn-(cereblon)
