CLEC9A (C-type lectin domain containing 9A)

2016-04-01  

Identity

HGNC
LOCATION
12p13.2
LOCUSID
ALIAS
CD370,DNGR-1,DNGR1,UNQ9341
FUSION GENES

Other Information

Locus ID:

NCBI: 283420
MIM: 612252
HGNC: 26705
Ensembl: ENSG00000197992

Variants:

dbSNP: 283420
ClinVar: 283420
TCGA: ENSG00000197992
COSMIC: CLEC9A

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000197992ENST00000355819Q6UXN8

Expression (GTEx)

0
1
2
3
4
5
6

References

Pubmed IDYearTitleCitations
359019212022Increased expression of Clec9A on cDC1s associated with cytotoxic CD8(+) T cell response in COPD.3
359019212022Increased expression of Clec9A on cDC1s associated with cytotoxic CD8(+) T cell response in COPD.3
333497082021The receptor DNGR-1 signals for phagosomal rupture to promote cross-presentation of dead-cell-associated antigens.65
340819222021Secreted gelsolin inhibits DNGR-1-dependent cross-presentation and cancer immunity.38
344150042021Expression of clec9a in the oral cancer microenvironment. A preliminary immunohistochemical pilot study.1
333497082021The receptor DNGR-1 signals for phagosomal rupture to promote cross-presentation of dead-cell-associated antigens.65
340819222021Secreted gelsolin inhibits DNGR-1-dependent cross-presentation and cancer immunity.38
344150042021Expression of clec9a in the oral cancer microenvironment. A preliminary immunohistochemical pilot study.1
290651392017CLEC9A modulates macrophage-mediated neutrophil recruitment in response to heat-killed Mycobacterium tuberculosis H37Ra.9
290651392017CLEC9A modulates macrophage-mediated neutrophil recruitment in response to heat-killed Mycobacterium tuberculosis H37Ra.9
272500272016A novel peptide targeting Clec9a on dendritic cell for cancer immunotherapy.30
272500272016A novel peptide targeting Clec9a on dendritic cell for cancer immunotherapy.30
249104482015BDCA3(+)CLEC9A(+) human dendritic cell function and development.33
249104482015BDCA3(+)CLEC9A(+) human dendritic cell function and development.33
240491502013Increased tubulointerstitial recruitment of human CD141(hi) CLEC9A(+) and CD1c(+) myeloid dendritic cell subsets in renal fibrosis and chronic kidney disease.35

Citation

Dessen P

CLEC9A (C-type lectin domain containing 9A)

Atlas Genet Cytogenet Oncol Haematol. 2016-04-01

Online version: http://atlasgeneticsoncology.org/gene/55695/clec9a-(c-type-lectin-domain-containing-9a)