Identity
HGNC
LOCATION
14q24.1
LOCUSID
ALIAS
C14orf114,EXDL2
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 55218
MIM: 616940
HGNC: 20217
Ensembl: ENSG00000081177
Variants:
dbSNP: 55218
ClinVar: 55218
TCGA: ENSG00000081177
COSMIC: EXD2
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 31127291 | 2019 | The structure of human EXD2 reveals a chimeric 3' to 5' exonuclease domain that discriminates substrates via metal coordination. | 9 |
| 31255466 | 2019 | EXD2 Protects Stressed Replication Forks and Is Required for Cell Viability in the Absence of BRCA1/2. | 17 |
| 31127291 | 2019 | The structure of human EXD2 reveals a chimeric 3' to 5' exonuclease domain that discriminates substrates via metal coordination. | 9 |
| 31255466 | 2019 | EXD2 Protects Stressed Replication Forks and Is Required for Cell Viability in the Absence of BRCA1/2. | 17 |
| 29599527 | 2018 | The mitochondrial outer-membrane location of the EXD2 exonuclease contradicts its direct role in nuclear DNA repair. | 8 |
| 29599527 | 2018 | The mitochondrial outer-membrane location of the EXD2 exonuclease contradicts its direct role in nuclear DNA repair. | 8 |
| 26807646 | 2016 | EXD2 promotes homologous recombination by facilitating DNA end resection. | 40 |
| 26807646 | 2016 | EXD2 promotes homologous recombination by facilitating DNA end resection. | 40 |
Citation
Dessen P
EXD2 (exonuclease 3-5 domain containing 2)
Atlas Genet Cytogenet Oncol Haematol. 2016-04-01
Online version: http://atlasgeneticsoncology.org/gene/55696/exd2-(exonuclease-3-5-domain-containing-2)
