Identity
HGNC
LOCATION
1p32.3
LOCUSID
ALIAS
AG1,AGR1,ERP16,ERP18,ERP19,PDIA16,TLP19,hAG-1,hTLP19
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 51060
MIM: 609448
HGNC: 24626
Ensembl: ENSG00000117862
Variants:
dbSNP: 51060
ClinVar: 51060
TCGA: ENSG00000117862
COSMIC: TXNDC12
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000117862 | ENST00000371626 | O95881 |
| ENSG00000117862 | ENST00000472624 | V9GYV4 |
| ENSG00000117862 | ENST00000610127 | V9GY50 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Glutathione metabolism | KEGG | ko00480 |
| Glutathione metabolism | KEGG | hsa00480 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 34629960 | 2021 | Clinical Value of TXNDC12 Combined With IDH and 1p19q as Biomarkers for Prognosis of Glioma. | 5 |
| 34629960 | 2021 | Clinical Value of TXNDC12 Combined With IDH and 1p19q as Biomarkers for Prognosis of Glioma. | 5 |
| 31570854 | 2020 | TXNDC12 promotes EMT and metastasis of hepatocellular carcinoma cells via activation of β-catenin. | 53 |
| 31570854 | 2020 | TXNDC12 promotes EMT and metastasis of hepatocellular carcinoma cells via activation of β-catenin. | 53 |
| 31368601 | 2019 | ERp18 regulates activation of ATF6α during unfolded protein response. | 34 |
| 31368601 | 2019 | ERp18 regulates activation of ATF6α during unfolded protein response. | 34 |
| 25940440 | 2015 | ERp19 contributes to tumorigenicity in human gastric cancer by promoting cell growth, migration and invasion. | 13 |
| 25940440 | 2015 | ERp19 contributes to tumorigenicity in human gastric cancer by promoting cell growth, migration and invasion. | 13 |
| 19361226 | 2009 | Solution structure and dynamics of ERp18, a small endoplasmic reticulum resident oxidoreductase . | 15 |
| 19887585 | 2009 | Protein disulphide isomerase family members show distinct substrate specificity: P5 is targeted to BiP client proteins. | 99 |
| 19361226 | 2009 | Solution structure and dynamics of ERp18, a small endoplasmic reticulum resident oxidoreductase . | 15 |
| 19887585 | 2009 | Protein disulphide isomerase family members show distinct substrate specificity: P5 is targeted to BiP client proteins. | 99 |
| 18628206 | 2008 | ERp16, an endoplasmic reticulum-resident thiol-disulfide oxidoreductase: biochemical properties and role in apoptosis induced by endoplasmic reticulum stress. | 16 |
| 18628206 | 2008 | ERp16, an endoplasmic reticulum-resident thiol-disulfide oxidoreductase: biochemical properties and role in apoptosis induced by endoplasmic reticulum stress. | 16 |
| 12761212 | 2003 | Functional characterization of ERp18, a new endoplasmic reticulum-located thioredoxin superfamily member. | 30 |
Citation
Dessen P
TXNDC12 (thioredoxin domain containing 12)
Atlas Genet Cytogenet Oncol Haematol. 2016-04-01
Online version: http://atlasgeneticsoncology.org/gene/55702/txndc12-(thioredoxin-domain-containing-12)
