Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 92797
MIM: 614539
HGNC: 17196
Ensembl: ENSG00000127311
Variants:
dbSNP: 92797
ClinVar: 92797
TCGA: ENSG00000127311
COSMIC: HELB
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000127311 | ENST00000247815 | Q8NG08 |
| ENSG00000127311 | ENST00000440906 | Q8NG08 |
| ENSG00000127311 | ENST00000542394 | F5H1I4 |
| ENSG00000127311 | ENST00000545134 | Q8NG08 |
Expression (GTEx)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35385349 | 2022 | Human HELB is a processive motor protein that catalyzes RPA clearance from single-stranded DNA. | 13 |
| 35385349 | 2022 | Human HELB is a processive motor protein that catalyzes RPA clearance from single-stranded DNA. | 13 |
| 32455610 | 2020 | Genome Maintenance by DNA Helicase B. | 9 |
| 32478505 | 2020 | The Expression of Human DNA Helicase B Is Affected by G-Quadruplexes in the Promoter. | 3 |
| 32455610 | 2020 | Genome Maintenance by DNA Helicase B. | 9 |
| 32478505 | 2020 | The Expression of Human DNA Helicase B Is Affected by G-Quadruplexes in the Promoter. | 3 |
| 26774285 | 2016 | HELB Is a Feedback Inhibitor of DNA End Resection. | 77 |
| 26774285 | 2016 | HELB Is a Feedback Inhibitor of DNA End Resection. | 77 |
| 25617833 | 2015 | Human DNA helicase B functions in cellular homologous recombination and stimulates Rad51-mediated 5'-3' heteroduplex extension in vitro. | 10 |
| 25933514 | 2015 | Human DNA helicase B interacts with the replication initiation protein Cdc45 and facilitates Cdc45 binding onto chromatin. | 13 |
| 25617833 | 2015 | Human DNA helicase B functions in cellular homologous recombination and stimulates Rad51-mediated 5'-3' heteroduplex extension in vitro. | 10 |
| 25933514 | 2015 | Human DNA helicase B interacts with the replication initiation protein Cdc45 and facilitates Cdc45 binding onto chromatin. | 13 |
| 22194613 | 2012 | Human DNA helicase B (HDHB) binds to replication protein A and facilitates cellular recovery from replication stress. | 30 |
| 22194613 | 2012 | Human DNA helicase B (HDHB) binds to replication protein A and facilitates cellular recovery from replication stress. | 30 |
| 12181327 | 2002 | A dominant-negative mutant of human DNA helicase B blocks the onset of chromosomal DNA replication. | 23 |
Citation
Dessen P
HELB (DNA helicase B)
Atlas Genet Cytogenet Oncol Haematol. 2016-04-01
Online version: http://atlasgeneticsoncology.org/gene/55703
