CALU (calumenin)

2016-04-01  

Identity

HGNC
LOCATION
7q32.1
LOCUSID
ALIAS
-
FUSION GENES

Other Information

Locus ID:

NCBI: 813
MIM: 603420
HGNC: 1458
Ensembl: ENSG00000128595

Variants:

dbSNP: 813
ClinVar: 813
TCGA: ENSG00000128595
COSMIC: CALU

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000128595ENST00000249364O43852
ENSG00000128595ENST00000249364Q6IAW5
ENSG00000128595ENST00000449187O43852
ENSG00000128595ENST00000449187A0A024R755
ENSG00000128595ENST00000479257O43852
ENSG00000128595ENST00000493278H0Y875
ENSG00000128595ENST00000535011O43852
ENSG00000128595ENST00000542996O43852

Expression (GTEx)

0
100
200
300
400
500
600
700

Pathways

PathwaySourceExternal ID
HemostasisREACTOMER-HSA-109582
Platelet activation, signaling and aggregationREACTOMER-HSA-76002
Response to elevated platelet cytosolic Ca2+REACTOMER-HSA-76005
Platelet degranulationREACTOMER-HSA-114608

Protein levels (Protein atlas)

Not detected
Low
Medium
High

PharmGKB

Entity IDNameTypeEvidenceAssociationPKPDPMIDs
PA28660GGCXGenePathwayassociated
PA451906warfarinChemicalClinicalAnnotation, VariantAnnotationambiguousPD19794411, 20200517, 21228733, 25126975
PA452632acenocoumarolChemicalClinicalAnnotationassociatedPD17596133, 29479633

References

Pubmed IDYearTitleCitations
324699832020Establishment of a CALU, AURKA, and MCM2 gene panel for discrimination of metastasis from primary colon and lung cancers.13
324699832020Establishment of a CALU, AURKA, and MCM2 gene panel for discrimination of metastasis from primary colon and lung cancers.13
293192982018The Differential Response to Ca(2+) from Vertebrate and Invertebrate Calumenin Is Governed by a Single Amino Acid Residue.0
293192982018The Differential Response to Ca(2+) from Vertebrate and Invertebrate Calumenin Is Governed by a Single Amino Acid Residue.0
281892672017Calumenin contributes to ER-Ca(2+) homeostasis in bronchial epithelial cells expressing WT and F508del mutated CFTR and to F508del-CFTR retention.6
281892672017Calumenin contributes to ER-Ca(2+) homeostasis in bronchial epithelial cells expressing WT and F508del mutated CFTR and to F508del-CFTR retention.6
277909162016Irradiation of Epithelial Carcinoma Cells Upregulates Calcium-Binding Proteins That Promote Survival under Hypoxic Conditions.8
277909162016Irradiation of Epithelial Carcinoma Cells Upregulates Calcium-Binding Proteins That Promote Survival under Hypoxic Conditions.8
258233962015CALU polymorphism A29809G affects calumenin availability involving vascular calcification.3
259638402015Identification and evaluation of metastasis-related proteins, oxysterol binding protein-like 5 and calumenin, in lung tumors.34
261242852015Quantitative Proteomics Reveals the Roles of Peroxisome-associated Proteins in Antiviral Innate Immune Responses.9
258233962015CALU polymorphism A29809G affects calumenin availability involving vascular calcification.3
259638402015Identification and evaluation of metastasis-related proteins, oxysterol binding protein-like 5 and calumenin, in lung tumors.34
261242852015Quantitative Proteomics Reveals the Roles of Peroxisome-associated Proteins in Antiviral Innate Immune Responses.9
251200072014Biophysical characterisation of calumenin as a charged F508del-CFTR folding modulator.3

Citation

Dessen P

CALU (calumenin)

Atlas Genet Cytogenet Oncol Haematol. 2016-04-01

Online version: http://atlasgeneticsoncology.org/gene/55704