SLC9A9 (solute carrier family 9 member A9)

2016-04-01  

Identity

HGNC
LOCATION
3q24
LOCUSID
ALIAS
AUTS16,NHE9
FUSION GENES

Other Information

Locus ID:

NCBI: 285195
MIM: 608396
HGNC: 20653
Ensembl: ENSG00000181804

Variants:

dbSNP: 285195
ClinVar: 285195
TCGA: ENSG00000181804
COSMIC: SLC9A9

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000181804ENST00000316549Q8IVB4
ENSG00000181804ENST00000474151C9IZP1
ENSG00000181804ENST00000474727F8WF83

Expression (GTEx)

0
5
10
15
20
25

Pathways

PathwaySourceExternal ID
Transmembrane transport of small moleculesREACTOMER-HSA-382551
SLC-mediated transmembrane transportREACTOMER-HSA-425407
Transport of inorganic cations/anions and amino acids/oligopeptidesREACTOMER-HSA-425393
Sodium/Proton exchangersREACTOMER-HSA-425986

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
389453112024Genes for endosomal pH regulators NHE6 and NHE9 are dysregulated in the substantia nigra in Parkinson's disease.0
389453112024Genes for endosomal pH regulators NHE6 and NHE9 are dysregulated in the substantia nigra in Parkinson's disease.0
324009532020Sodium hydrogen exchanger 9 NHE9 (SLC9A9) and its emerging roles in neuropsychiatric comorbidity.4
331186342020Structure and elevator mechanism of the mammalian sodium/proton exchanger NHE9.26
324009532020Sodium hydrogen exchanger 9 NHE9 (SLC9A9) and its emerging roles in neuropsychiatric comorbidity.4
331186342020Structure and elevator mechanism of the mammalian sodium/proton exchanger NHE9.26
309272342019Effect of disease-associated SLC9A9 mutations on protein-protein interaction networks: implications for molecular mechanisms for ADHD and autism.8
309272342019Effect of disease-associated SLC9A9 mutations on protein-protein interaction networks: implications for molecular mechanisms for ADHD and autism.8
274395722017SLC9A9 Co-expression modules in autism-associated brain regions.4
277665362017Genetic Variants and Multiple Sclerosis Risk Gene SLC9A9 Expression in Distinct Human Brain Regions.19
281304432017Na(+)/H(+) Exchanger 9 Regulates Iron Mobilization at the Blood-Brain Barrier in Response to Iron Starvation.18
284767902017Up-regulation of SLC9A9 Promotes Cancer Progression and Is Involved in Poor Prognosis in Colorectal Cancer.8
292687742017MicroRNA-135a regulates NHE9 to inhibit proliferation and migration of glioblastoma cells.19
274395722017SLC9A9 Co-expression modules in autism-associated brain regions.4
277665362017Genetic Variants and Multiple Sclerosis Risk Gene SLC9A9 Expression in Distinct Human Brain Regions.19

Citation

Dessen P

SLC9A9 (solute carrier family 9 member A9)

Atlas Genet Cytogenet Oncol Haematol. 2016-04-01

Online version: http://atlasgeneticsoncology.org/gene/55706/slc9a9-(solute-carrier-family-9-member-a9)