Identity
HGNC
LOCATION
6p21.33
LOCUSID
ALIAS
DDAH,DDAHII,G6a,HEL-S-277,NG30
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 23564
MIM: 604744
HGNC: 2716
Ensembl: ENSG00000213722
Variants:
dbSNP: 23564
ClinVar: 23564
TCGA: ENSG00000213722
COSMIC: DDAH2
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Metabolism | REACTOME | R-HSA-1430728 |
| Metabolism of nitric oxide | REACTOME | R-HSA-202131 |
| eNOS activation and regulation | REACTOME | R-HSA-203765 |
| eNOS activation | REACTOME | R-HSA-203615 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38765527 | 2024 | Early and late-onset preeclampsia: effects of DDAH2 polymorphisms on ADMA levels and association with DDAH2 haplotypes. | 0 |
| 38765527 | 2024 | Early and late-onset preeclampsia: effects of DDAH2 polymorphisms on ADMA levels and association with DDAH2 haplotypes. | 0 |
| 36233204 | 2022 | Assessment of DDAH1 and DDAH2 Contributions to Psychiatric Disorders via In Silico Methods. | 0 |
| 36233204 | 2022 | Assessment of DDAH1 and DDAH2 Contributions to Psychiatric Disorders via In Silico Methods. | 0 |
| 34283907 | 2021 | Polymorphism (-499C/G) in DDAH2 promoter may act as a protective factor for metabolic syndrome: A case-control study in Azar-Cohort population. | 0 |
| 34283907 | 2021 | Polymorphism (-499C/G) in DDAH2 promoter may act as a protective factor for metabolic syndrome: A case-control study in Azar-Cohort population. | 0 |
| 31409409 | 2019 | A functional variant of the dimethylarginine dimethylaminohydrolase-2 gene is associated with myocardial infarction in type 2 diabetic patients. | 4 |
| 31409409 | 2019 | A functional variant of the dimethylarginine dimethylaminohydrolase-2 gene is associated with myocardial infarction in type 2 diabetic patients. | 4 |
| 30538005 | 2018 | Evidence for a protective role for the rs805305 single nucleotide polymorphism of dimethylarginine dimethylaminohydrolase 2 (DDAH2) in septic shock through the regulation of DDAH activity. | 6 |
| 30538005 | 2018 | Evidence for a protective role for the rs805305 single nucleotide polymorphism of dimethylarginine dimethylaminohydrolase 2 (DDAH2) in septic shock through the regulation of DDAH activity. | 6 |
| 28150318 | 2017 | Determine exogenous human DDAH2 gene function in rabbit bone marrow-derived endothelial progenitor cells in vitro. | 2 |
| 28590543 | 2017 | Association of the -449GC and -1151AC polymorphisms in the DDAH2 gene with asymmetric dimethylarginine and erythropoietin resistance in Chinese patients on maintenance hemodialysis. | 5 |
| 28150318 | 2017 | Determine exogenous human DDAH2 gene function in rabbit bone marrow-derived endothelial progenitor cells in vitro. | 2 |
| 28590543 | 2017 | Association of the -449GC and -1151AC polymorphisms in the DDAH2 gene with asymmetric dimethylarginine and erythropoietin resistance in Chinese patients on maintenance hemodialysis. | 5 |
| 26515557 | 2016 | Dimethylarginine dimethylaminohydrolase 2 promotes tumor angiogenesis in lung adenocarcinoma. | 10 |
Citation
Dessen P
DDAH2 (dimethylarginine dimethylaminohydrolase 2)
Atlas Genet Cytogenet Oncol Haematol. 2016-04-01
Online version: http://atlasgeneticsoncology.org/gene/55719/ddah2-(dimethylarginine-dimethylaminohydrolase-2)
