SUSD4 (sushi domain containing 4)

2016-04-01  

Identity

HGNC
SUSD4
LOCATION
1q41
LOCUSID
55061
ALIAS
PRO222
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 55061
MIM: 615827
HGNC: 25470
Ensembl: ENSG00000143502

Variants:

dbSNP: 55061
ClinVar: 55061
TCGA: ENSG00000143502
COSMIC: SUSD4

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000143502ENST00000343846Q5VX71
ENSG00000143502ENST00000344029Q5VX71
ENSG00000143502ENST00000344029A0A140VK55
ENSG00000143502ENST00000366878Q5VX71
ENSG00000143502ENST00000484758B7Z369
ENSG00000143502ENST00000494793V9GYN8
ENSG00000143502ENST00000608996V9GZ49

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
50
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
385791742024Pan-cancer analysis of Sushi domain-containing protein 4 (SUSD4) and validated in colorectal cancer.0
385791742024Pan-cancer analysis of Sushi domain-containing protein 4 (SUSD4) and validated in colorectal cancer.0
365780142022Sushi domain-containing protein 4 binds to epithelial growth factor receptor and initiates autophagy in an EGFR phosphorylation independent manner.1
365780142022Sushi domain-containing protein 4 binds to epithelial growth factor receptor and initiates autophagy in an EGFR phosphorylation independent manner.1
264808182015The human complement inhibitor Sushi Domain-Containing Protein 4 (SUSD4) expression in tumor cells and infiltrating T cells is associated with better prognosis of breast cancer patients.6
264808182015The human complement inhibitor Sushi Domain-Containing Protein 4 (SUSD4) expression in tumor cells and infiltrating T cells is associated with better prognosis of breast cancer patients.6
234826362013Sushi domain-containing protein 4 (SUSD4) inhibits complement by disrupting the formation of the classical C3 convertase.18
234826362013Sushi domain-containing protein 4 (SUSD4) inhibits complement by disrupting the formation of the classical C3 convertase.18
202374962010New genetic associations detected in a host response study to hepatitis B vaccine.37
203482462010Tissue distribution and functional analysis of Sushi domain-containing protein 4.8
202374962010New genetic associations detected in a host response study to hepatitis B vaccine.37
203482462010Tissue distribution and functional analysis of Sushi domain-containing protein 4.8

Citation

Dessen P

SUSD4 (sushi domain containing 4)

Atlas Genet Cytogenet Oncol Haematol. 2016-04-01

Online version: http://atlasgeneticsoncology.org/gene/55725/susd4-(sushi-domain-containing-4)