KREMEN1 (kringle containing transmembrane protein 1)

2016-04-01  

Identity

HGNC
LOCATION
22q12.1
LOCUSID
ALIAS
ECTD13,KREMEN,KRM1
FUSION GENES

Other Information

Locus ID:

NCBI: 83999
MIM: 609898
HGNC: 17550
Ensembl: ENSG00000183762

Variants:

dbSNP: 83999
ClinVar: 83999
TCGA: ENSG00000183762
COSMIC: KREMEN1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000183762ENST00000327813Q96MU8
ENSG00000183762ENST00000400335Q96MU8
ENSG00000183762ENST00000407188Q96MU8
ENSG00000183762ENST00000453585H7BZ87

Expression (GTEx)

0
5
10
15
20
25
30
35
40

Pathways

PathwaySourceExternal ID
DiseaseREACTOMER-HSA-1643685
Diseases of signal transductionREACTOMER-HSA-5663202
Signaling by WNT in cancerREACTOMER-HSA-4791275
Misspliced LRP5 mutants have enhanced beta-catenin-dependent signalingREACTOMER-HSA-5339717
Signal TransductionREACTOMER-HSA-162582
Signaling by WntREACTOMER-HSA-195721
TCF dependent signaling in response to WNTREACTOMER-HSA-201681
Negative regulation of TCF-dependent signaling by WNT ligand antagonistsREACTOMER-HSA-3772470

References

Pubmed IDYearTitleCitations
340289422022Novel homozygous KREMEN1 mutation causes ectodermal dysplasia.0
348370592022Receptome profiling identifies KREMEN1 and ASGR1 as alternative functional receptors of SARS-CoV-2.85
349038542022Novel SARS-CoV-2 receptors: ASGR1 and KREMEN1.0
340289422022Novel homozygous KREMEN1 mutation causes ectodermal dysplasia.0
348370592022Receptome profiling identifies KREMEN1 and ASGR1 as alternative functional receptors of SARS-CoV-2.85
349038542022Novel SARS-CoV-2 receptors: ASGR1 and KREMEN1.0
325210042021Replication of 15 loci involved in human plasma protein N-glycosylation in 4802 samples from four cohorts.7
325210042021Replication of 15 loci involved in human plasma protein N-glycosylation in 4802 samples from four cohorts.7
319116012020Hand-foot-and-mouth disease virus receptor KREMEN1 binds the canyon of Coxsackie Virus A10.22
326906972020Molecular basis of Coxsackievirus A10 entry using the two-in-one attachment and uncoating receptor KRM1.13
319116012020Hand-foot-and-mouth disease virus receptor KREMEN1 binds the canyon of Coxsackie Virus A10.22
326906972020Molecular basis of Coxsackievirus A10 entry using the two-in-one attachment and uncoating receptor KRM1.13
314471192019Knockdown of lncRNA SNHG1 attenuated Aβ(25-35)-inudced neuronal injury via regulating KREMEN1 by acting as a ceRNA of miR-137 in neuronal cells.0
314471192019Knockdown of lncRNA SNHG1 attenuated Aβ(25-35)-inudced neuronal injury via regulating KREMEN1 by acting as a ceRNA of miR-137 in neuronal cells.0
295260312018Novel compound heterozygous mutations in KREMEN1 confirm it as a disease gene for ectodermal dysplasia.5

Citation

Dessen P

KREMEN1 (kringle containing transmembrane protein 1)

Atlas Genet Cytogenet Oncol Haematol. 2016-04-01

Online version: http://atlasgeneticsoncology.org/gene/55727/gene-fusions/deep-insight-explorer/