CLIC5 (chloride intracellular channel 5)

2016-04-01  

Identity

HGNC
CLIC5
LOCATION
6p21.1
LOCUSID
53405
ALIAS
DFNB102,DFNB103,MST130,MSTP130
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 53405
MIM: 607293
HGNC: 13517
Ensembl: ENSG00000112782

Variants:

dbSNP: 53405
ClinVar: 53405
TCGA: ENSG00000112782
COSMIC: CLIC5

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000112782ENST00000185206Q9NZA1
ENSG00000112782ENST00000339561Q9NZA1
ENSG00000112782ENST00000339561Q53G01
ENSG00000112782ENST00000544153Q9NZA1
ENSG00000112782ENST00000642250A0A2R8YGW2
ENSG00000112782ENST00000644324A0A2R8Y615
ENSG00000112782ENST00000644878A0A2R8Y4M1

Expression (GTEx)

0
10
20
30
40
50
60
70
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
372867342023A comprehensively prognostic and immunological analysis of chloride intracellular channel protein 5 (CLIC5) in pan-cancer and identification in ovarian cancer.1
372867342023A comprehensively prognostic and immunological analysis of chloride intracellular channel protein 5 (CLIC5) in pan-cancer and identification in ovarian cancer.1
331141132020Bi-Allelic Novel Variants in CLIC5 Identified in a Cameroonian Multiplex Family with Non-Syndromic Hearing Impairment.7
331141132020Bi-Allelic Novel Variants in CLIC5 Identified in a Cameroonian Multiplex Family with Non-Syndromic Hearing Impairment.7
275401362016CLIC5: a novel ETV6 target gene in childhood acute lymphoblastic leukemia.15
275401362016CLIC5: a novel ETV6 target gene in childhood acute lymphoblastic leukemia.15
247817542015Progressive hearing loss and vestibular dysfunction caused by a homozygous nonsense mutation in CLIC5.27
261353982015Co-Expression of Ezrin-CLIC5-Podocalyxin Is Associated with Migration and Invasiveness in Hepatocellular Carcinoma.25
247817542015Progressive hearing loss and vestibular dysfunction caused by a homozygous nonsense mutation in CLIC5.27
261353982015Co-Expression of Ezrin-CLIC5-Podocalyxin Is Associated with Migration and Invasiveness in Hepatocellular Carcinoma.25
253442522014Clustered PI(4,5)P₂ accumulation and ezrin phosphorylation in response to CLIC5A.15
253442522014Clustered PI(4,5)P₂ accumulation and ezrin phosphorylation in response to CLIC5A.15
203353152010CLIC5A, a component of the ezrin-podocalyxin complex in glomeruli, is a determinant of podocyte integrity.30
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
203353152010CLIC5A, a component of the ezrin-podocalyxin complex in glomeruli, is a determinant of podocyte integrity.30

Citation

Dessen P

CLIC5 (chloride intracellular channel 5)

Atlas Genet Cytogenet Oncol Haematol. 2016-04-01

Online version: http://atlasgeneticsoncology.org/gene/55730/clic5-(chloride-intracellular-channel-5)