Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 145270
MIM: 613851
HGNC: 18319
Ensembl: ENSG00000175785
Variants:
dbSNP: 145270
ClinVar: 145270
TCGA: ENSG00000175785
COSMIC: PRIMA1
RNA/Proteins
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 30602570 | 2019 | p53 reactivation with induction of massive apoptosis-1 (PRIMA-1) inhibits amyloid aggregation of mutant p53 in cancer cells. | 38 |
| 30602570 | 2019 | p53 reactivation with induction of massive apoptosis-1 (PRIMA-1) inhibits amyloid aggregation of mutant p53 in cancer cells. | 38 |
| 28753106 | 2017 | Colorectal adenoma and cancer detection based on altered methylation pattern of SFRP1, SFRP2, SDC2, and PRIMA1 in plasma samples. | 58 |
| 28753106 | 2017 | Colorectal adenoma and cancer detection based on altered methylation pattern of SFRP1, SFRP2, SDC2, and PRIMA1 in plasma samples. | 58 |
| 26712693 | 2016 | Silencing of CD24 Enhances the PRIMA-1-Induced Restoration of Mutant p53 in Prostate Cancer Cells. | 17 |
| 26742039 | 2016 | Aberrant DNA Methylation of rDNA and PRIMA1 in Borderline Personality Disorder. | 8 |
| 27533450 | 2016 | PRIMA-1 targets the vulnerability of multiple myeloma of deregulated protein homeostasis through the perturbation of ER stress via p73 demethylation. | 19 |
| 26712693 | 2016 | Silencing of CD24 Enhances the PRIMA-1-Induced Restoration of Mutant p53 in Prostate Cancer Cells. | 17 |
| 26742039 | 2016 | Aberrant DNA Methylation of rDNA and PRIMA1 in Borderline Personality Disorder. | 8 |
| 27533450 | 2016 | PRIMA-1 targets the vulnerability of multiple myeloma of deregulated protein homeostasis through the perturbation of ER stress via p73 demethylation. | 19 |
| 26482433 | 2015 | DNA hypermethylation and decreased mRNA expression of MAL, PRIMA1, PTGDR and SFRP1 in colorectal adenoma and cancer. | 34 |
| 26482433 | 2015 | DNA hypermethylation and decreased mRNA expression of MAL, PRIMA1, PTGDR and SFRP1 in colorectal adenoma and cancer. | 34 |
| 23545415 | 2013 | PRIMA-1 induces autophagy in cancer cells carrying mutant or wild type p53. | 15 |
| 23545415 | 2013 | PRIMA-1 induces autophagy in cancer cells carrying mutant or wild type p53. | 15 |
| 22750213 | 2012 | N-linked glycosylation of proline-rich membrane anchor (PRiMA) is not required for assembly and trafficking of globular tetrameric acetylcholinesterase. | 3 |
Citation
Dessen P
PRIMA1 (proline rich membrane anchor 1)
Atlas Genet Cytogenet Oncol Haematol. 2016-04-01
Online version: http://atlasgeneticsoncology.org/gene/55735/prima1-(proline-rich-membrane-anchor-1)
