Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 203190
MIM: 608302
HGNC: 18711
Ensembl: ENSG00000168481
Variants:
dbSNP: 203190
ClinVar: 203190
TCGA: ENSG00000168481
COSMIC: LGI3
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000168481 | ENST00000306317 | Q8N145 |
| ENSG00000168481 | ENST00000424267 | Q8N145 |
| ENSG00000168481 | ENST00000517694 | H0YAP4 |
| ENSG00000168481 | ENST00000518365 | E5RIV5 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Developmental Biology | REACTOME | R-HSA-1266738 |
| LGI-ADAM interactions | REACTOME | R-HSA-5682910 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35751164 | 2022 | LGI3 promotes human keratinocyte migration in high-glucose environments by increasing the expression of β-catenin. | 2 |
| 35751164 | 2022 | LGI3 promotes human keratinocyte migration in high-glucose environments by increasing the expression of β-catenin. | 2 |
| 31627033 | 2020 | LGI3 is secreted and binds to ADAM22 via TRIF-dependent NF-κB pathway in response to LPS in human keratinocytes. | 4 |
| 31627033 | 2020 | LGI3 is secreted and binds to ADAM22 via TRIF-dependent NF-κB pathway in response to LPS in human keratinocytes. | 4 |
| 29257304 | 2018 | Leucine-rich glioma inactivated 3: Integrative analyses reveal its potential prognostic role in cancer. | 5 |
| 30091803 | 2018 | LGI3 promotes human keratinocyte differentiation via the Akt pathway. | 8 |
| 29257304 | 2018 | Leucine-rich glioma inactivated 3: Integrative analyses reveal its potential prognostic role in cancer. | 5 |
| 30091803 | 2018 | LGI3 promotes human keratinocyte differentiation via the Akt pathway. | 8 |
| 24903553 | 2014 | Leucine-rich glioma inactivated 3 is a melanogenic cytokine in human skin. | 7 |
| 24903553 | 2014 | Leucine-rich glioma inactivated 3 is a melanogenic cytokine in human skin. | 7 |
| 23815230 | 2013 | Leucine-rich glioma inactivated 3 promotes HaCaT keratinocyte migration. | 10 |
| 23815230 | 2013 | Leucine-rich glioma inactivated 3 promotes HaCaT keratinocyte migration. | 10 |
Citation
Dessen P
LGI3 (leucine rich repeat LGI family member 3)
Atlas Genet Cytogenet Oncol Haematol. 2016-05-01
Online version: http://atlasgeneticsoncology.org/gene/55756/lgi3-(leucine-rich-repeat-lgi-family-member-3)
