Identity
HGNC
LOCATION
22q12.2
LOCUSID
ALIAS
PRP21,PRPF21,SAP114,SF3A120
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 10291
MIM: 605595
HGNC: 10765
Ensembl: ENSG00000099995
Variants:
dbSNP: 10291
ClinVar: 10291
TCGA: ENSG00000099995
COSMIC: SF3A1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37094335 | 2023 | Structural insights into recognition of SL4, the UUCG stem-loop, of human U1 snRNA by the ubiquitin-like domain, including the C-terminal tail in the SF3A1 subunit of U2 snRNP. | 1 |
| 37094335 | 2023 | Structural insights into recognition of SL4, the UUCG stem-loop, of human U1 snRNA by the ubiquitin-like domain, including the C-terminal tail in the SF3A1 subunit of U2 snRNP. | 1 |
| 31383795 | 2019 | Identification of a noncanonical RNA binding domain in the U2 snRNP protein SF3A1. | 13 |
| 31383795 | 2019 | Identification of a noncanonical RNA binding domain in the U2 snRNP protein SF3A1. | 13 |
| 26079486 | 2015 | The Associations between RNA Splicing Complex Gene SF3A1 Polymorphisms and Colorectal Cancer Risk in a Chinese Population. | 6 |
| 26498691 | 2015 | SF3A1 and pancreatic cancer: new evidence for the association of the spliceosome and cancer. | 10 |
| 26079486 | 2015 | The Associations between RNA Splicing Complex Gene SF3A1 Polymorphisms and Colorectal Cancer Risk in a Chinese Population. | 6 |
| 26498691 | 2015 | SF3A1 and pancreatic cancer: new evidence for the association of the spliceosome and cancer. | 10 |
| 25403181 | 2014 | Stem-loop 4 of U1 snRNA is essential for splicing and interacts with the U2 snRNP-specific SF3A1 protein during spliceosome assembly. | 37 |
| 25403181 | 2014 | Stem-loop 4 of U1 snRNA is essential for splicing and interacts with the U2 snRNP-specific SF3A1 protein during spliceosome assembly. | 37 |
| 24204290 | 2013 | Limiting of the innate immune response by SF3A-dependent control of MyD88 alternative mRNA splicing. | 50 |
| 24204290 | 2013 | Limiting of the innate immune response by SF3A-dependent control of MyD88 alternative mRNA splicing. | 50 |
| 20379614 | 2010 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | 78 |
| 20379614 | 2010 | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. | 78 |
| 15647371 | 2005 | Human splicing factor SF3a, but not SF1, is essential for pre-mRNA splicing in vivo. | 79 |
Citation
Dessen P
SF3A1 (splicing factor 3a subunit 1)
Atlas Genet Cytogenet Oncol Haematol. 2016-05-01
Online version: http://atlasgeneticsoncology.org/gene/55762/gene-explorer/meetings/new-content/
