Identity
HGNC
LOCATION
16q24.2
LOCUSID
ALIAS
FOG,FOG1,ZC2HC11A,ZNF408,ZNF89A
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 161882
MIM: 601950
HGNC: 19762
Ensembl: ENSG00000179588
Variants:
dbSNP: 161882
ClinVar: 161882
TCGA: ENSG00000179588
COSMIC: ZFPM1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000179588 | ENST00000319555 | Q8IX07 |
| ENSG00000179588 | ENST00000562437 | A0A087WWQ0 |
| ENSG00000179588 | ENST00000563351 | A0A087X1H8 |
| ENSG00000179588 | ENST00000569086 | A0A087WZP1 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Hemostasis | REACTOME | R-HSA-109582 |
| Factors involved in megakaryocyte development and platelet production | REACTOME | R-HSA-983231 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38757931 | 2024 | PI3K/HSCB axis facilitates FOG1 nuclear translocation to promote erythropoiesis and megakaryopoiesis. | 0 |
| 38757931 | 2024 | PI3K/HSCB axis facilitates FOG1 nuclear translocation to promote erythropoiesis and megakaryopoiesis. | 0 |
| 35690555 | 2022 | The upregulation of Gata transcription factors family and FOG-1 in expanded and differentiated cord blood-derived CD34(+) hematopoietic stem cells to megakaryocyte lineage during co-culture with cord blood mesenchymal stem cells. | 0 |
| 35690555 | 2022 | The upregulation of Gata transcription factors family and FOG-1 in expanded and differentiated cord blood-derived CD34(+) hematopoietic stem cells to megakaryocyte lineage during co-culture with cord blood mesenchymal stem cells. | 0 |
| 32561925 | 2020 | Long Noncoding RNA ZFPM2-AS1 Knockdown Restrains the Development of Retinoblastoma by Modulating the MicroRNA-515/HOXA1/Wnt/β-Catenin Axis. | 11 |
| 32561925 | 2020 | Long Noncoding RNA ZFPM2-AS1 Knockdown Restrains the Development of Retinoblastoma by Modulating the MicroRNA-515/HOXA1/Wnt/β-Catenin Axis. | 11 |
| 28216155 | 2017 | Forced FOG1 expression in erythroleukemia cells: Induction of erythroid genes and repression of myelo-lymphoid transcription factor PU.1. | 3 |
| 28216155 | 2017 | Forced FOG1 expression in erythroleukemia cells: Induction of erythroid genes and repression of myelo-lymphoid transcription factor PU.1. | 3 |
| 26503584 | 2015 | Identification of four new susceptibility loci for testicular germ cell tumour. | 21 |
| 26503584 | 2015 | Identification of four new susceptibility loci for testicular germ cell tumour. | 21 |
| 25162672 | 2014 | The identification and structure of an N-terminal PR domain show that FOG1 is a member of the PRDM family of proteins. | 6 |
| 25165715 | 2014 | Lead discovery for Alzheimer's disease related target protein RbAp48 from traditional Chinese medicine. | 4 |
| 25162672 | 2014 | The identification and structure of an N-terminal PR domain show that FOG1 is a member of the PRDM family of proteins. | 6 |
| 25165715 | 2014 | Lead discovery for Alzheimer's disease related target protein RbAp48 from traditional Chinese medicine. | 4 |
| 24179092 | 2013 | Friend of GATA and GATA-6 modulate the transcriptional up-regulation of hepcidin in hepatocytes during inflammation. | 6 |
Citation
Dessen P
ZFPM1 (zinc finger protein, FOG family member 1)
Atlas Genet Cytogenet Oncol Haematol. 2016-05-01
Online version: http://atlasgeneticsoncology.org/gene/55763/zfpm1-(zinc-finger-protein-fog-family-member-1)
