FATE1 (fetal and adult testis expressed 1)

2016-05-01  

Identity

HGNC
FATE1
LOCATION
Xq28
LOCUSID
89885
ALIAS
CT43,FATE
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 89885
MIM: 300450
HGNC: 24683
Ensembl: ENSG00000147378

Variants:

dbSNP: 89885
ClinVar: 89885
TCGA: ENSG00000147378
COSMIC: FATE1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000147378ENST00000370350Q969F0
ENSG00000147378ENST00000417321H7C1I5

Expression (GTEx)

0
100
200
300
400
500
600
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
310365662019EWSR1-FLI1 Activation of the Cancer/Testis Antigen FATE1 Promotes Ewing Sarcoma Survival.11
310365662019EWSR1-FLI1 Activation of the Cancer/Testis Antigen FATE1 Promotes Ewing Sarcoma Survival.11
274025442016FATE1 antagonizes calcium- and drug-induced apoptosis by uncoupling ER and mitochondria.55
274025442016FATE1 antagonizes calcium- and drug-induced apoptosis by uncoupling ER and mitochondria.55
265678492015Comprehensive functional characterization of cancer-testis antigens defines obligate participation in multiple hallmarks of cancer.61
265678492015Comprehensive functional characterization of cancer-testis antigens defines obligate participation in multiple hallmarks of cancer.61
128115412003Mutational analysis of the human FATE gene in 144 infertile men.4
128115412003Mutational analysis of the human FATE gene in 144 infertile men.4

Citation

Dessen P

FATE1 (fetal and adult testis expressed 1)

Atlas Genet Cytogenet Oncol Haematol. 2016-05-01

Online version: http://atlasgeneticsoncology.org/gene/55770/fate1-(fetal-and-adult-testis-expressed-1)