PRMT9 (protein arginine methyltransferase 9)

2016-05-01  

Identity

HGNC
LOCATION
4q31.23
LOCUSID
ALIAS
PRMT10
FUSION GENES

Other Information

Locus ID:

NCBI: 90826
MIM: 616125
HGNC: 25099
Ensembl: ENSG00000164169

Variants:

dbSNP: 90826
ClinVar: 90826
TCGA: ENSG00000164169
COSMIC: PRMT9

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000164169ENST00000322396Q6P2P2
ENSG00000164169ENST00000514886D6REN0

Expression (GTEx)

0
5
10
15
20
25
30
35

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
385613342024Loss-of-function mutation in PRMT9 causes abnormal synapse development by dysregulation of RNA alternative splicing.0
385613342024Loss-of-function mutation in PRMT9 causes abnormal synapse development by dysregulation of RNA alternative splicing.0
377152212023Arginine methylation of HSPA8 by PRMT9 inhibits ferroptosis to accelerate hepatitis B virus-associated hepatocellular carcinoma progression.4
377152212023Arginine methylation of HSPA8 by PRMT9 inhibits ferroptosis to accelerate hepatitis B virus-associated hepatocellular carcinoma progression.4
360284842022The protein arginine methyltransferase PRMT9 attenuates MAVS activation through arginine methylation.14
360284842022The protein arginine methyltransferase PRMT9 attenuates MAVS activation through arginine methylation.14
296038302018PRMT9 promotes hepatocellular carcinoma invasion and metastasis via activating PI3K/Akt/GSK-3β/Snail signaling.55
296038302018PRMT9 promotes hepatocellular carcinoma invasion and metastasis via activating PI3K/Akt/GSK-3β/Snail signaling.55
279112652017MiRNA-543 promotes osteosarcoma cell proliferation and glycolysis by partially suppressing PRMT9 and stabilizing HIF-1α protein.30
279112652017MiRNA-543 promotes osteosarcoma cell proliferation and glycolysis by partially suppressing PRMT9 and stabilizing HIF-1α protein.30
257370132015PRMT9 is a type II methyltransferase that methylates the splicing factor SAP145.98
257990062015Protein arginine methyltransferase 10 is required for androgen-dependent proliferation of LNCaP prostate cancer cells.0
259793442015Unique Features of Human Protein Arginine Methyltransferase 9 (PRMT9) and Its Substrate RNA Splicing Factor SF3B2.54
257370132015PRMT9 is a type II methyltransferase that methylates the splicing factor SAP145.98
257990062015Protein arginine methyltransferase 10 is required for androgen-dependent proliferation of LNCaP prostate cancer cells.0

Citation

Dessen P

PRMT9 (protein arginine methyltransferase 9)

Atlas Genet Cytogenet Oncol Haematol. 2016-05-01

Online version: http://atlasgeneticsoncology.org/gene/55771/prmt9-(protein-arginine-methyltransferase-9)