Identity
HGNC
LOCATION
12p13.31
LOCUSID
ALIAS
AZ3B,C3AR,HNFAG09
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 719
MIM: 605246
HGNC: 1319
Ensembl: ENSG00000171860
Variants:
dbSNP: 719
ClinVar: 719
TCGA: ENSG00000171860
COSMIC: C3AR1
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000171860 | ENST00000307637 | Q16581 |
| ENSG00000171860 | ENST00000307637 | A8K2H7 |
| ENSG00000171860 | ENST00000546241 | F5GZE6 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37909169 | 2024 | Deficiency of Complement C3a and C5a receptors Does Not Prevent Angiotensin II-Induced Hypertension and Hypertensive End-Organ Damage. | 1 |
| 38227377 | 2024 | C3aR-initiated signaling is a critical mechanism of podocyte injury in membranous nephropathy. | 0 |
| 37909169 | 2024 | Deficiency of Complement C3a and C5a receptors Does Not Prevent Angiotensin II-Induced Hypertension and Hypertensive End-Organ Damage. | 1 |
| 38227377 | 2024 | C3aR-initiated signaling is a critical mechanism of podocyte injury in membranous nephropathy. | 0 |
| 35220210 | 2022 | The Complement C3a-C3a Receptor Axis Regulates Epithelial-to-Mesenchymal Transition by Activating the ERK Pathway in Pancreatic Ductal Adenocarcinoma. | 7 |
| 36521939 | 2022 | Molecular signatures of intrarenal complement receptors C3AR1 and C5AR1 correlate with renal outcome in human lupus nephritis. | 3 |
| 35220210 | 2022 | The Complement C3a-C3a Receptor Axis Regulates Epithelial-to-Mesenchymal Transition by Activating the ERK Pathway in Pancreatic Ductal Adenocarcinoma. | 7 |
| 36521939 | 2022 | Molecular signatures of intrarenal complement receptors C3AR1 and C5AR1 correlate with renal outcome in human lupus nephritis. | 3 |
| 33306149 | 2021 | Changes in VGF and C3aR1 gene expression in human adipose tissue in obesity. | 7 |
| 33446393 | 2021 | Autoantibodies against C5aR1, C3aR1, CXCR3, and CXCR4 are decreased in primary Sjogren's syndrome. | 2 |
| 33539329 | 2021 | High Expression of the Component 3a Receptor 1 (C3AR1) Gene in Stomach Adenocarcinomas Infers a Poor Prognosis and High Immune-Infiltration Levels. | 12 |
| 33746964 | 2021 | Mitochondrial C3a Receptor Activation in Oxidatively Stressed Epithelial Cells Reduces Mitochondrial Respiration and Metabolism. | 20 |
| 34162127 | 2021 | Identification and characterization of prognosis-related genes in the tumor microenvironment of esophageal squamous cell carcinoma. | 5 |
| 33306149 | 2021 | Changes in VGF and C3aR1 gene expression in human adipose tissue in obesity. | 7 |
| 33446393 | 2021 | Autoantibodies against C5aR1, C3aR1, CXCR3, and CXCR4 are decreased in primary Sjogren's syndrome. | 2 |
Citation
Dessen P
C3AR1 (complement C3a receptor 1)
Atlas Genet Cytogenet Oncol Haematol. 2016-05-01
Online version: http://atlasgeneticsoncology.org/gene/55773/c3ar1-(complement-c3a-receptor-1)
