PPFIBP2 (PPFIA binding protein 2)

2016-05-01 Affiliation

Identity

HGNC

PPFIBP2

LOCATION

11p15.4

LOCUSID

8495

ALIAS

Cclp1

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 8495
MIM: 603142
HGNC: 9250
Ensembl: ENSG00000166387

Variants:

dbSNP: 8495
ClinVar: 8495
TCGA: ENSG00000166387
COSMIC: PPFIBP2

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000166387	ENST00000299492	Q8ND30
ENSG00000166387	ENST00000524548	H0YDM0
ENSG00000166387	ENST00000525597	E9PJA0
ENSG00000166387	ENST00000526046	E9PMN3
ENSG00000166387	ENST00000526873	E9PK17
ENSG00000166387	ENST00000527790	E9PMH3
ENSG00000166387	ENST00000528883	Q8ND30
ENSG00000166387	ENST00000528947	E9PK17
ENSG00000166387	ENST00000529575	E9PIK8
ENSG00000166387	ENST00000530081	E9PI79
ENSG00000166387	ENST00000530181	Q8ND30
ENSG00000166387	ENST00000533792	E9PP16
ENSG00000166387	ENST00000534409	H0YDJ2
ENSG00000166387	ENST00000534552	H0YET1
ENSG00000166387	ENST00000650027	A0A3B3IS15

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Protein levels (Protein atlas)

Not detected

Low

Medium

High

References

Pubmed ID	Year	Title	Citations
30043417	2018	Germline mutations in PPFIBP2 are associated with lethal prostate cancer.	8
30043417	2018	Germline mutations in PPFIBP2 are associated with lethal prostate cancer.	8
26663347	2016	Effects of the scaffold proteins liprin-α1, β1 and β2 on invasion by breast cancer cells.	18
26663347	2016	Effects of the scaffold proteins liprin-α1, β1 and β2 on invasion by breast cancer cells.	18
26443449	2015	Large-scale association analysis in Asians identifies new susceptibility loci for prostate cancer.	35
26443449	2015	Large-scale association analysis in Asians identifies new susceptibility loci for prostate cancer.	35
22328529	2012	ERK2 drives tumour cell migration in three-dimensional microenvironments by suppressing expression of Rab17 and liprin-β2.	40
22328529	2012	ERK2 drives tumour cell migration in three-dimensional microenvironments by suppressing expression of Rab17 and liprin-β2.	40
21462929	2011	Crystal structure of the central coiled-coil domain from human liprin-β2.	4
21462929	2011	Crystal structure of the central coiled-coil domain from human liprin-β2.	4
20095854	2010	Novel breast cancer risk alleles and interaction with ionizing radiation among U.S. radiologic technologists.	23
20379614	2010	Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.	78
20095854	2010	Novel breast cancer risk alleles and interaction with ionizing radiation among U.S. radiologic technologists.	23
20379614	2010	Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.	78

Citation

Dessen P

PPFIBP2 (PPFIA binding protein 2)

Atlas Genet Cytogenet Oncol Haematol. 2016-05-01

Online version: http://atlasgeneticsoncology.org/gene/55776/ppfibp2-(ppfia-binding-protein-2)