Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9215
MIM: 603590
HGNC: 6511
Ensembl: ENSG00000133424
Variants:
dbSNP: 9215
ClinVar: 9215
TCGA: ENSG00000133424
COSMIC: LARGE1
RNA/Proteins
Expression (GTEx)
Pathways
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33588034 | 2021 | Clinical significance of LARGE1 in progression of liver cancer and the underlying mechanism. | 1 |
| 34452470 | 2021 | The Origins and Future of Sentinel: An Early-Warning System for Pandemic Preemption and Response. | 4 |
| 33588034 | 2021 | Clinical significance of LARGE1 in progression of liver cancer and the underlying mechanism. | 1 |
| 34452470 | 2021 | The Origins and Future of Sentinel: An Early-Warning System for Pandemic Preemption and Response. | 4 |
| 31054580 | 2019 | Exogenous expression of the glycosyltransferase LARGE1 restores α-dystroglycan matriglycan and laminin binding in rhabdomyosarcoma. | 7 |
| 31054580 | 2019 | Exogenous expression of the glycosyltransferase LARGE1 restores α-dystroglycan matriglycan and laminin binding in rhabdomyosarcoma. | 7 |
| 27636103 | 2017 | Common fragile sites (CFS) and extremely large CFS genes are targets for human papillomavirus integrations and chromosome rearrangements in oropharyngeal squamous cell carcinoma. | 27 |
| 27636103 | 2017 | Common fragile sites (CFS) and extremely large CFS genes are targets for human papillomavirus integrations and chromosome rearrangements in oropharyngeal squamous cell carcinoma. | 27 |
| 24629698 | 2014 | Correlation of deregulated like-acetylglucosaminyl transferase and aberrant α-dystroglycan expression with human tongue cancer metastasis. | 8 |
| 24709677 | 2014 | Clinical, pathologic, and mutational spectrum of dystroglycanopathy caused by LARGE mutations. | 16 |
| 25279697 | 2014 | B4GAT1 is the priming enzyme for the LARGE-dependent functional glycosylation of α-dystroglycan. | 50 |
| 25279699 | 2014 | The glucuronyltransferase B4GAT1 is required for initiation of LARGE-mediated α-dystroglycan functional glycosylation. | 62 |
| 24629698 | 2014 | Correlation of deregulated like-acetylglucosaminyl transferase and aberrant α-dystroglycan expression with human tongue cancer metastasis. | 8 |
| 24709677 | 2014 | Clinical, pathologic, and mutational spectrum of dystroglycanopathy caused by LARGE mutations. | 16 |
| 25279697 | 2014 | B4GAT1 is the priming enzyme for the LARGE-dependent functional glycosylation of α-dystroglycan. | 50 |
Citation
Dessen P
LARGE1 (LARGE xylosyl- and glucuronyltransferase 1)
Atlas Genet Cytogenet Oncol Haematol. 2016-06-01
Online version: http://atlasgeneticsoncology.org/gene/55802/new-content/gene-fusions-explorer/
