ERO1B (endoplasmic reticulum oxidoreductase 1 beta)

2016-06-01  

Identity

HGNC
LOCATION
1q42.3
LOCUSID
ALIAS
ERO1LB,Ero1beta

Other Information

Locus ID:

NCBI: 56605
MIM: 615437
HGNC: 14355
Ensembl: ENSG00000086619

Variants:

dbSNP: 56605
ClinVar: 56605
TCGA: ENSG00000086619
COSMIC: ERO1B

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000086619ENST00000264181Q5TAE8
ENSG00000086619ENST00000354619Q86YB8
ENSG00000086619ENST00000366589Q5T1H5

Expression (GTEx)

0
10
20
30
40
50
60
70
80
90
100

Pathways

PathwaySourceExternal ID
Protein processing in endoplasmic reticulumKEGGko04141
Protein processing in endoplasmic reticulumKEGGhsa04141
Metabolism of proteinsREACTOMER-HSA-392499
Peptide hormone metabolismREACTOMER-HSA-2980736
Insulin processingREACTOMER-HSA-264876

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
310290322019ATF6α Activation Enhances Survival against Chemotherapy and Serves as a Prognostic Indicator in Osteosarcoma.11
310290322019ATF6α Activation Enhances Survival against Chemotherapy and Serves as a Prognostic Indicator in Osteosarcoma.11
281779042017Genome-scale analysis identifies GJB2 and ERO1LB as prognosis markers in patients with pancreatic cancer.35
281779042017Genome-scale analysis identifies GJB2 and ERO1LB as prognosis markers in patients with pancreatic cancer.35
267654692016The Immunohistochemical Evaluation of Solid Pseudopapillary Tumors of the Pancreas and Pancreatic Neuroendocrine Tumors Reveals ERO1Lβ as a New Biomarker.4
267654692016The Immunohistochemical Evaluation of Solid Pseudopapillary Tumors of the Pancreas and Pancreatic Neuroendocrine Tumors Reveals ERO1Lβ as a New Biomarker.4
279190372014Biochemical evidence that regulation of Ero1β activity in human cells does not involve the isoform-specific cysteine 262.3
279190372014Biochemical evidence that regulation of Ero1β activity in human cells does not involve the isoform-specific cysteine 262.3
210914352011The endoplasmic reticulum sulfhydryl oxidase Ero1β drives efficient oxidative protein folding with loose regulation.29
210914352011The endoplasmic reticulum sulfhydryl oxidase Ero1β drives efficient oxidative protein folding with loose regulation.29
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
189967532009Response of adiponectin and its receptors to changes in metabolic state after gastric bypass surgery: dissociation between adipose tissue expression and circulating levels.5
197306832009The variant rs1867277 in FOXE1 gene confers thyroid cancer susceptibility through the recruitment of USF1/USF2 transcription factors.74
189967532009Response of adiponectin and its receptors to changes in metabolic state after gastric bypass surgery: dissociation between adipose tissue expression and circulating levels.5

Citation

Dessen P

ERO1B (endoplasmic reticulum oxidoreductase 1 beta)

Atlas Genet Cytogenet Oncol Haematol. 2016-06-01

Online version: http://atlasgeneticsoncology.org/gene/55814/ero1b-(endoplasmic-reticulum-oxidoreductase-1-beta)