Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 120071
MIM: 609709
HGNC: 16522
Ensembl: ENSG00000165905
Variants:
dbSNP: 120071
ClinVar: 120071
TCGA: ENSG00000165905
COSMIC: LARGE2
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 32586342 | 2020 | Wnt-driven LARGE2 mediates laminin-adhesive O-glycosylation in human colonic epithelial cells and colorectal cancer. | 10 |
| 32586342 | 2020 | Wnt-driven LARGE2 mediates laminin-adhesive O-glycosylation in human colonic epithelial cells and colorectal cancer. | 10 |
| 25455932 | 2015 | The glycosyltransferase LARGE2 is repressed by Snail and ZEB1 in prostate cancer. | 11 |
| 26220087 | 2015 | Downregulation of dystroglycan glycosyltransferases LARGE2 and ISPD associate with increased mortality in clear cell renal cell carcinoma. | 11 |
| 25455932 | 2015 | The glycosyltransferase LARGE2 is repressed by Snail and ZEB1 in prostate cancer. | 11 |
| 26220087 | 2015 | Downregulation of dystroglycan glycosyltransferases LARGE2 and ISPD associate with increased mortality in clear cell renal cell carcinoma. | 11 |
| 23223448 | 2013 | Loss of LARGE2 disrupts functional glycosylation of α-dystroglycan in prostate cancer. | 26 |
| 23223448 | 2013 | Loss of LARGE2 disrupts functional glycosylation of α-dystroglycan in prostate cancer. | 26 |
| 19851296 | 2010 | Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals. | 7 |
| 20198315 | 2010 | Association of genetic variants with hemorrhagic stroke in Japanese individuals. | 17 |
| 19851296 | 2010 | Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals. | 7 |
| 20198315 | 2010 | Association of genetic variants with hemorrhagic stroke in Japanese individuals. | 17 |
| 19724895 | 2009 | Association of gene polymorphisms with chronic kidney disease in Japanese individuals. | 0 |
| 19724895 | 2009 | Association of gene polymorphisms with chronic kidney disease in Japanese individuals. | 0 |
| 15752776 | 2005 | LARGE2 facilitates the maturation of alpha-dystroglycan more effectively than LARGE. | 28 |
Citation
Dessen P
LARGE2 (LARGE xylosyl- and glucuronyltransferase 2)
Atlas Genet Cytogenet Oncol Haematol. 2016-06-01
Online version: http://atlasgeneticsoncology.org/gene/55818/large2-(large-xylosyl-and-glucuronyltransferase-2)
