Identity
HGNC
LOCATION
11q13.5
LOCUSID
ALIAS
CPPRDD,D11S833E,GARP
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 2615
MIM: 137207
HGNC: 4161
Ensembl: ENSG00000137507
Variants:
dbSNP: 2615
ClinVar: 2615
TCGA: ENSG00000137507
COSMIC: LRRC32
RNA/Proteins
Expression (GTEx)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38698265 | 2024 | Suppression of lysosome metabolism-meditated GARP/TGF-β1 complexes specifically depletes regulatory T cells to inhibit breast cancer metastasis. | 0 |
| 38698265 | 2024 | Suppression of lysosome metabolism-meditated GARP/TGF-β1 complexes specifically depletes regulatory T cells to inhibit breast cancer metastasis. | 0 |
| 36683084 | 2023 | Analysis of LAP(+) and GARP(+) Treg subsets in peripheral blood of patients with neuromyelitis optica spectrum disorders. | 1 |
| 36683084 | 2023 | Analysis of LAP(+) and GARP(+) Treg subsets in peripheral blood of patients with neuromyelitis optica spectrum disorders. | 1 |
| 36460874 | 2022 | New insight into GARP striking role in cancer progression: application for cancer therapy. | 2 |
| 36460874 | 2022 | New insight into GARP striking role in cancer progression: application for cancer therapy. | 2 |
| 34059789 | 2021 | Dysregulated immunity in PID patients with low GARP expression on Tregs due to mutations in LRRC32. | 8 |
| 34235533 | 2021 | Novel anti-GARP antibody DS-1055a augments anti-tumor immunity by depleting highly suppressive GARP+ regulatory T cells. | 7 |
| 34421887 | 2021 | GARP Correlates With Tumor-Infiltrating T-Cells and Predicts the Outcome of Gastric Cancer. | 12 |
| 34059789 | 2021 | Dysregulated immunity in PID patients with low GARP expression on Tregs due to mutations in LRRC32. | 8 |
| 34235533 | 2021 | Novel anti-GARP antibody DS-1055a augments anti-tumor immunity by depleting highly suppressive GARP+ regulatory T cells. | 7 |
| 34421887 | 2021 | GARP Correlates With Tumor-Infiltrating T-Cells and Predicts the Outcome of Gastric Cancer. | 12 |
| 31812328 | 2020 | Genetic variants of the C11orf30-LRRC32 region are associated with childhood asthma in the Chinese population. | 3 |
| 31915300 | 2020 | Thrombin contributes to cancer immune evasion via proteolysis of platelet-bound GARP to activate LTGF-β. | 50 |
| 32375042 | 2020 | The Parkinson's Disease Protein LRRK2 Interacts with the GARP Complex to Promote Retrograde Transport to the trans-Golgi Network. | 29 |
Citation
Dessen P
LRRC32 (leucine rich repeat containing 32)
Atlas Genet Cytogenet Oncol Haematol. 2016-08-01
Online version: http://atlasgeneticsoncology.org/gene/55825/lrrc32-(leucine-rich-repeat-containing-32)
