Identity
HGNC
LOCATION
11q13.2
LOCUSID
ALIAS
GTRAP41,SCA5,SCAR14
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 6712
MIM: 604985
HGNC: 11276
Ensembl: ENSG00000173898
Variants:
dbSNP: 6712
ClinVar: 6712
TCGA: ENSG00000173898
COSMIC: SPTBN2
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38241838 | 2024 | SPTBN2 suppresses ferroptosis in NSCLC cells by facilitating SLC7A11 membrane trafficking and localization. | 1 |
| 38241838 | 2024 | SPTBN2 suppresses ferroptosis in NSCLC cells by facilitating SLC7A11 membrane trafficking and localization. | 1 |
| 37626910 | 2023 | Increased Actin Binding Is a Shared Molecular Consequence of Numerous SCA5 Mutations in β-III-Spectrin. | 0 |
| 38279463 | 2023 | SPTBN2 regulated by miR-214-3p inhibits the proliferation and migration of colorectal cancer cells. | 1 |
| 37626910 | 2023 | Increased Actin Binding Is a Shared Molecular Consequence of Numerous SCA5 Mutations in β-III-Spectrin. | 0 |
| 38279463 | 2023 | SPTBN2 regulated by miR-214-3p inhibits the proliferation and migration of colorectal cancer cells. | 1 |
| 35968508 | 2022 | SPTBN2 Promotes the Progression of Thyroid Cancer by Accelerating G1/S Transition and Inhibiting Apoptosis. | 2 |
| 35968508 | 2022 | SPTBN2 Promotes the Progression of Thyroid Cancer by Accelerating G1/S Transition and Inhibiting Apoptosis. | 2 |
| 33797620 | 2021 | Two novel missense variants in SPTBN2 likely associated with spinocerebellar ataxia type 5. | 6 |
| 33801522 | 2021 | Expanding the β-III Spectrin-Associated Phenotypes toward Non-Progressive Congenital Ataxias with Neurodegeneration. | 9 |
| 33797620 | 2021 | Two novel missense variants in SPTBN2 likely associated with spinocerebellar ataxia type 5. | 6 |
| 33801522 | 2021 | Expanding the β-III Spectrin-Associated Phenotypes toward Non-Progressive Congenital Ataxias with Neurodegeneration. | 9 |
| 30798076 | 2019 | Utilization of spectrins βI and βIII in diagnosis of hepatocellular carcinoma. | 2 |
| 30798076 | 2019 | Utilization of spectrins βI and βIII in diagnosis of hepatocellular carcinoma. | 2 |
| 29196973 | 2018 | A Novel Homozygous Mutation in SPTBN2 Leads to Spinocerebellar Ataxia in a Consanguineous Family: Report of a New Infantile-Onset Case and Brief Review of the Literature. | 9 |
Citation
Dessen P
SPTBN2 (spectrin beta, non-erythrocytic 2)
Atlas Genet Cytogenet Oncol Haematol. 2016-08-01
Online version: http://atlasgeneticsoncology.org/gene/55829/sptbn2-(spectrin-beta-non-erythrocytic-2)
