Identity
HGNC
LOCATION
4q31.1
LOCUSID
ALIAS
CAGH3,ERDA3,GDN,MAM-2,MAM2,TNRC3,mam-3
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 55534
MIM: 608991
HGNC: 16272
Ensembl: ENSG00000196782
Variants:
dbSNP: 55534
ClinVar: 55534
TCGA: ENSG00000196782
COSMIC: MAML3
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000196782 | ENST00000398940 | E7ESR8 |
| ENSG00000196782 | ENST00000502696 | H0Y920 |
| ENSG00000196782 | ENST00000509479 | Q96JK9 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37351966 | 2023 | MAML3 Contributes to Induction of Malignant Phenotype of Gallbladder Cancer Through Morphogenesis Signalling Under Hypoxia. | 0 |
| 37351966 | 2023 | MAML3 Contributes to Induction of Malignant Phenotype of Gallbladder Cancer Through Morphogenesis Signalling Under Hypoxia. | 0 |
| 33986121 | 2021 | Mastermind Like Transcriptional Coactivator 3 (MAML3) Drives Neuroendocrine Tumor Progression. | 12 |
| 33986121 | 2021 | Mastermind Like Transcriptional Coactivator 3 (MAML3) Drives Neuroendocrine Tumor Progression. | 12 |
| 30061220 | 2018 | RBPJ and MAML3: Potential Therapeutic Targets for Small Cell Lung Cancer. | 7 |
| 30061220 | 2018 | RBPJ and MAML3: Potential Therapeutic Targets for Small Cell Lung Cancer. | 7 |
| 27709636 | 2017 | PTTG1IP and MAML3, novel genomewide association study genes for severity of hyperresponsiveness in adult asthma. | 9 |
| 28512191 | 2017 | MiR-2392 suppresses metastasis and epithelial-mesenchymal transition by targeting MAML3 and WHSC1 in gastric cancer. | 16 |
| 27709636 | 2017 | PTTG1IP and MAML3, novel genomewide association study genes for severity of hyperresponsiveness in adult asthma. | 9 |
| 28512191 | 2017 | MiR-2392 suppresses metastasis and epithelial-mesenchymal transition by targeting MAML3 and WHSC1 in gastric cancer. | 16 |
| 26655998 | 2016 | Hypoxia but not normoxia promotes Smoothened transcription through upregulation of RBPJ and Mastermind-like 3 in pancreatic cancer. | 11 |
| 26752546 | 2016 | Novel BCOR-MAML3 and ZC3H7B-BCOR Gene Fusions in Undifferentiated Small Blue Round Cell Sarcomas. | 48 |
| 26785999 | 2016 | Mastermind-Like 3 Controls Proliferation and Differentiation in Neuroblastoma. | 14 |
| 27466498 | 2016 | Protein-bound Polysaccharide-K Inhibits Hedgehog Signaling Through Down-regulation of MAML3 and RBPJ Transcription Under Hypoxia, Suppressing the Malignant Phenotype in Pancreatic Cancer. | 8 |
| 26655998 | 2016 | Hypoxia but not normoxia promotes Smoothened transcription through upregulation of RBPJ and Mastermind-like 3 in pancreatic cancer. | 11 |
Citation
Dessen P
MAML3 (mastermind like transcriptional coactivator 3)
Atlas Genet Cytogenet Oncol Haematol. 2016-08-01
Online version: http://atlasgeneticsoncology.org/gene/55830/maml3-(mastermind-like-transcriptional-coactivator-3)
