Identity
HGNC
LOCATION
20p11.23
LOCUSID
ALIAS
CHED,CHED1,CHED2,EUROIMAGE566589,PPCD1,ZNF339
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 58495
MIM: 616441
HGNC: 15804
Ensembl: ENSG00000125850
Variants:
dbSNP: 58495
ClinVar: 58495
TCGA: ENSG00000125850
COSMIC: OVOL2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000125850 | ENST00000278780 | Q9BRP0 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37971355 | 2024 | Ovol2 promoter mutations in mice and human illuminate species-specific phenotypic divergence. | 1 |
| 37971355 | 2024 | Ovol2 promoter mutations in mice and human illuminate species-specific phenotypic divergence. | 1 |
| 34033850 | 2022 | OVOL2 inhibits macrophage M2 polarization by regulating IL-10 transcription, and thus inhibits the tumor metastasis by modulating the tumor microenvironment. | 5 |
| 34469340 | 2022 | c.-61G>A in OVOL2 is a Pathogenic 5' Untranslated Region Variant Causing Posterior Polymorphous Corneal Dystrophy 1. | 2 |
| 35337349 | 2022 | OVOL2 impairs RHO GTPase signaling to restrain mitosis and aggressiveness of Anaplastic Thyroid Cancer. | 5 |
| 35346238 | 2022 | An NF-κB/OVOL2 circuit regulates glucose import and cell survival in non-small cell lung cancer. | 5 |
| 35896951 | 2022 | Transcriptional Repression of Aerobic Glycolysis by OVOL2 in Breast Cancer. | 12 |
| 34033850 | 2022 | OVOL2 inhibits macrophage M2 polarization by regulating IL-10 transcription, and thus inhibits the tumor metastasis by modulating the tumor microenvironment. | 5 |
| 34469340 | 2022 | c.-61G>A in OVOL2 is a Pathogenic 5' Untranslated Region Variant Causing Posterior Polymorphous Corneal Dystrophy 1. | 2 |
| 35337349 | 2022 | OVOL2 impairs RHO GTPase signaling to restrain mitosis and aggressiveness of Anaplastic Thyroid Cancer. | 5 |
| 35346238 | 2022 | An NF-κB/OVOL2 circuit regulates glucose import and cell survival in non-small cell lung cancer. | 5 |
| 35896951 | 2022 | Transcriptional Repression of Aerobic Glycolysis by OVOL2 in Breast Cancer. | 12 |
| 33989778 | 2021 | Dysregulation of the Pdx1/Ovol2/Zeb2 axis in dedifferentiated β-cells triggers the induction of genes associated with epithelial-mesenchymal transition in diabetes. | 7 |
| 34098198 | 2021 | OVOL2 attenuates the expression of MAP3K8 to suppress epithelial mesenchymal transition in colorectal cancer. | 3 |
| 34984648 | 2021 | Altered Epithelial-mesenchymal Plasticity as a Result of Ovol2 Deletion Minimally Impacts the Self-renewal of Adult Mammary Basal Epithelial Cells. | 1 |
Citation
Dessen P
OVOL2 (ovo like zinc finger 2)
Atlas Genet Cytogenet Oncol Haematol. 2016-08-01
Online version: http://atlasgeneticsoncology.org/gene/55831/deep-insight-explorer/
