Identity
HGNC
LOCATION
7q31.32
LOCUSID
ALIAS
C-LMOD,CLMOD
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 442721
MIM: 608006
HGNC: 6648
Ensembl: ENSG00000170807
Variants:
dbSNP: 442721
ClinVar: 442721
TCGA: ENSG00000170807
COSMIC: LMOD2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000170807 | ENST00000456238 | C9J8F4 |
| ENSG00000170807 | ENST00000458573 | Q6P5Q4 |
Expression (GTEx)
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 38748723 | 2024 | Human disease-causing mutations result in loss of leiomodin 2 through nonsense-mediated mRNA decay. | 0 |
| 38748723 | 2024 | Human disease-causing mutations result in loss of leiomodin 2 through nonsense-mediated mRNA decay. | 0 |
| 37296576 | 2023 | Whole-Exome Sequencing Identifies Homozygote Nonsense Variants in LMOD2 Gene Causing Infantile Dilated Cardiomyopathy. | 3 |
| 37296576 | 2023 | Whole-Exome Sequencing Identifies Homozygote Nonsense Variants in LMOD2 Gene Causing Infantile Dilated Cardiomyopathy. | 3 |
| 31517052 | 2019 | Disruption of cardiac thin filament assembly arising from a mutation in LMOD2: A novel mechanism of neonatal dilated cardiomyopathy. | 22 |
| 31517052 | 2019 | Disruption of cardiac thin filament assembly arising from a mutation in LMOD2: A novel mechanism of neonatal dilated cardiomyopathy. | 22 |
| 28834725 | 2017 | Crystal Structure of Leiomodin 2 in Complex with Actin: A Structural and Functional Reexamination. | 9 |
| 28834725 | 2017 | Crystal Structure of Leiomodin 2 in Complex with Actin: A Structural and Functional Reexamination. | 9 |
| 26873245 | 2016 | Localization of the binding interface between leiomodin-2 and α-tropomyosin. | 16 |
| 26873245 | 2016 | Localization of the binding interface between leiomodin-2 and α-tropomyosin. | 16 |
| 26370058 | 2015 | How Leiomodin and Tropomodulin use a common fold for different actin assembly functions. | 32 |
| 26417072 | 2015 | Mechanisms of leiomodin 2-mediated regulation of actin filament in muscle cells. | 21 |
| 26370058 | 2015 | How Leiomodin and Tropomodulin use a common fold for different actin assembly functions. | 32 |
| 26417072 | 2015 | Mechanisms of leiomodin 2-mediated regulation of actin filament in muscle cells. | 21 |
| 18403713 | 2008 | Leiomodin is an actin filament nucleator in muscle cells. | 144 |
Citation
Dessen P
LMOD2 (leiomodin 2)
Atlas Genet Cytogenet Oncol Haematol. 2016-08-01
Online version: http://atlasgeneticsoncology.org/gene/55840/lmod2-(leiomodin-2)
