Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9027
MIM: 606716
HGNC: 18069
Ensembl: ENSG00000144035
Variants:
dbSNP: 9027
ClinVar: 9027
TCGA: ENSG00000144035
COSMIC: NAT8
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000144035 | ENST00000272425 | Q9UHE5 |
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Glutathione metabolism | KEGG | ko00480 |
| Glutathione metabolism | KEGG | hsa00480 |
| Metabolism of proteins | REACTOME | R-HSA-392499 |
| Amyloid fiber formation | REACTOME | R-HSA-977225 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 35170979 | 2022 | N-Acetyltransferase 8 Promotes Viral Replication by Increasing the Stability of Enterovirus 71 Nonstructural Proteins. | 7 |
| 35170979 | 2022 | N-Acetyltransferase 8 Promotes Viral Replication by Increasing the Stability of Enterovirus 71 Nonstructural Proteins. | 7 |
| 33380473 | 2020 | NAT8 Variants, N-Acetylated Amino Acids, and Progression of CKD. | 15 |
| 33380473 | 2020 | NAT8 Variants, N-Acetylated Amino Acids, and Progression of CKD. | 15 |
| 26819345 | 2016 | Role of Increased n-acetylaspartate Levels in Cancer. | 36 |
| 26819345 | 2016 | Role of Increased n-acetylaspartate Levels in Cancer. | 36 |
| 25301944 | 2014 | The endoplasmic reticulum-based acetyltransferases, ATase1 and ATase2, associate with the oligosaccharyltransferase to acetylate correctly folded polypeptides. | 15 |
| 25301944 | 2014 | The endoplasmic reticulum-based acetyltransferases, ATase1 and ATase2, associate with the oligosaccharyltransferase to acetylate correctly folded polypeptides. | 15 |
| 22267734 | 2012 | Biochemical inhibition of the acetyltransferases ATase1 and ATase2 reduces β-secretase (BACE1) levels and Aβ generation. | 22 |
| 22267734 | 2012 | Biochemical inhibition of the acetyltransferases ATase1 and ATase2 reduces β-secretase (BACE1) levels and Aβ generation. | 22 |
| 20383145 | 2010 | Genetic loci influencing kidney function and chronic kidney disease. | 136 |
| 20385109 | 2010 | Methamphetamine-induced neuronal protein NAT8L is the NAA biosynthetic enzyme: implications for specialized acetyl coenzyme A metabolism in the CNS. | 41 |
| 20392701 | 2010 | Molecular identification of NAT8 as the enzyme that acetylates cysteine S-conjugates to mercapturic acids. | 35 |
| 20383145 | 2010 | Genetic loci influencing kidney function and chronic kidney disease. | 136 |
| 20385109 | 2010 | Methamphetamine-induced neuronal protein NAT8L is the NAA biosynthetic enzyme: implications for specialized acetyl coenzyme A metabolism in the CNS. | 41 |
Citation
Dessen P
NAT8 (N-acetyltransferase 8 (putative))
Atlas Genet Cytogenet Oncol Haematol. 2016-08-01
Online version: http://atlasgeneticsoncology.org/gene/55841/nat8-(n-acetyltransferase-8-(putative))
