RAB11FIP2 (RAB11 family interacting protein 2)

2016-08-01  

Identity

HGNC
LOCATION
10q26.11
LOCUSID
ALIAS
Rab11-FIP2,nRip11
FUSION GENES

Other Information

Locus ID:

NCBI: 22841
MIM: 608599
HGNC: 29152
Ensembl: ENSG00000107560

Variants:

dbSNP: 22841
ClinVar: 22841
TCGA: ENSG00000107560
COSMIC: RAB11FIP2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000107560ENST00000355624Q7L804
ENSG00000107560ENST00000369199Q7L804

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45

Pathways

PathwaySourceExternal ID
EndocytosisKEGGko04144
EndocytosisKEGGhsa04144
Transmembrane transport of small moleculesREACTOMER-HSA-382551
Aquaporin-mediated transportREACTOMER-HSA-445717
Vasopressin regulates renal water homeostasis via AquaporinsREACTOMER-HSA-432040

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
314522572020Knockdown Rab11-FIP2 inhibits migration and invasion of nasopharyngeal carcinoma via suppressing Rho GTPase signaling.2
327442472020Crystal structure of the Rab-binding domain of Rab11 family-interacting protein 2.1
314522572020Knockdown Rab11-FIP2 inhibits migration and invasion of nasopharyngeal carcinoma via suppressing Rho GTPase signaling.2
327442472020Crystal structure of the Rab-binding domain of Rab11 family-interacting protein 2.1
304718662019Rab11-FIP2 suppressed tumor growth via regulation of PGK1 ubiquitination in non-small cell lung cancer.11
306591202019The integral function of the endocytic recycling compartment is regulated by RFFL-mediated ubiquitylation of Rab11 effectors.13
304718662019Rab11-FIP2 suppressed tumor growth via regulation of PGK1 ubiquitination in non-small cell lung cancer.11
306591202019The integral function of the endocytic recycling compartment is regulated by RFFL-mediated ubiquitylation of Rab11 effectors.13
300065182018Inhibition of the miR-192/215-Rab11-FIP2 axis suppresses human gastric cancer progression.13
300065182018Inhibition of the miR-192/215-Rab11-FIP2 axis suppresses human gastric cancer progression.13
280738332017Exosomal miR-142-3p is increased during cardiac allograft rejection and augments vascular permeability through down-regulation of endothelial RAB11FIP2 expression.36
282285502017Interaction of phosphorylated Rab11-FIP2 with Eps15 regulates apical junction composition.3
280738332017Exosomal miR-142-3p is increased during cardiac allograft rejection and augments vascular permeability through down-regulation of endothelial RAB11FIP2 expression.36
282285502017Interaction of phosphorylated Rab11-FIP2 with Eps15 regulates apical junction composition.3
265020902016Rab11-FIP2 promotes the metastasis of gastric cancer cells.20

Citation

Dessen P

RAB11FIP2 (RAB11 family interacting protein 2)

Atlas Genet Cytogenet Oncol Haematol. 2016-08-01

Online version: http://atlasgeneticsoncology.org/gene/55843/rab11fip2-(rab11-family-interacting-protein-2)