SYCP2 (synaptonemal complex protein 2)

2016-08-01   Dessen P  

Identity

HGNC
SYCP2
LOCATION
20q13.33
LOCUSID
10388
ALIAS
SCP-2,SCP2,SPGF1
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 10388
MIM: 604105
HGNC: 11490
Ensembl: ENSG00000196074

Variants:

dbSNP: 10388
ClinVar: 10388
TCGA: ENSG00000196074
COSMIC: SYCP2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000196074ENST00000357552Q9BX26
ENSG00000196074ENST00000371001Q9BX26
ENSG00000196074ENST00000412613A2A340
ENSG00000196074ENST00000425931A2A2M9
ENSG00000196074ENST00000446834A2A341

Expression (GTEx)

0
5
10
15
20
25
30
35
40
45
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Cell CycleREACTOMER-HSA-1640170
MeiosisREACTOMER-HSA-1500620
Meiotic synapsisREACTOMER-HSA-1221632

References

Pubmed IDYearTitleCitations
318660472020SYCP2 Translocation-Mediated Dysregulation and Frameshift Variants Cause Human Male Infertility.36
318660472020SYCP2 Translocation-Mediated Dysregulation and Frameshift Variants Cause Human Male Infertility.36
263346522015Deregulation of SYCP2 predicts early stage human papillomavirus-positive oropharyngeal carcinoma: A prospective whole transcriptome analysis.31
263346522015Deregulation of SYCP2 predicts early stage human papillomavirus-positive oropharyngeal carcinoma: A prospective whole transcriptome analysis.31
203786152010Evaluation of 172 candidate polymorphisms for association with oligozoospermia or azoospermia in a large cohort of men of European descent.61
203786152010Evaluation of 172 candidate polymorphisms for association with oligozoospermia or azoospermia in a large cohort of men of European descent.61

Citation

Dessen P

SYCP2 (synaptonemal complex protein 2)

Atlas Genet Cytogenet Oncol Haematol. 2016-08-01

Online version: http://atlasgeneticsoncology.org/gene/55846/sycp2-(synaptonemal-complex-protein-2)