TCEA3 (transcription elongation factor A3)

2016-08-01  

Identity

HGNC
LOCATION
1p36.12
LOCUSID
ALIAS
TFIIS,TFIIS.H
FUSION GENES

Other Information

Locus ID:

NCBI: 6920
MIM: 604128
HGNC: 11615
Ensembl: ENSG00000204219

Variants:

dbSNP: 6920
ClinVar: 6920
TCGA: ENSG00000204219
COSMIC: TCEA3

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000204219ENST00000374601O75764
ENSG00000204219ENST00000450454O75764
ENSG00000204219ENST00000461794S4R419
ENSG00000204219ENST00000476978S4R3M9

Expression (GTEx)

0
50
100
150
200

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
319883072020The transcription elongation factor TCEA3 induces apoptosis in rhabdomyosarcoma.6
319883072020The transcription elongation factor TCEA3 induces apoptosis in rhabdomyosarcoma.6
270055222016TFIIS.h, a new target of p53, regulates transcription efficiency of pro-apoptotic bax gene.6
270055222016TFIIS.h, a new target of p53, regulates transcription efficiency of pro-apoptotic bax gene.6
264986642015TCEA3 Attenuates Gastric Cancer Growth by Apoptosis Induction.7
264986642015TCEA3 Attenuates Gastric Cancer Growth by Apoptosis Induction.7
233575332013TCEA3 binds to TGF-beta receptor I and induces Smad-independent, JNK-dependent apoptosis in ovarian cancer cells.20
233575332013TCEA3 binds to TGF-beta receptor I and induces Smad-independent, JNK-dependent apoptosis in ovarian cancer cells.20
201787422010The human PAF1 complex acts in chromatin transcription elongation both independently and cooperatively with SII/TFIIS.159
206280862010Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.15
201787422010The human PAF1 complex acts in chromatin transcription elongation both independently and cooperatively with SII/TFIIS.159
206280862010Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.15
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.105
199131212009Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.105

Citation

Dessen P

TCEA3 (transcription elongation factor A3)

Atlas Genet Cytogenet Oncol Haematol. 2016-08-01

Online version: http://atlasgeneticsoncology.org/gene/55847/tcea3-(transcription-elongation-factor-a3)