Identity
HGNC
LOCATION
9q34.13
LOCUSID
ALIAS
CRAP34,CRSP34,CRSP8,MED3,NEDSCAC,TRAP37
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 9442
MIM: 605044
HGNC: 2377
Ensembl: ENSG00000160563
Variants:
dbSNP: 9442
ClinVar: 9442
TCGA: ENSG00000160563
COSMIC: MED27
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36786527 | 2023 | MED27 plays a tumor-promoting role in breast cancer progression by targeting KLF4. | 2 |
| 37517035 | 2023 | Biallelic MED27 variants lead to variable ponto-cerebello-lental degeneration with movement disorders. | 0 |
| 36786527 | 2023 | MED27 plays a tumor-promoting role in breast cancer progression by targeting KLF4. | 2 |
| 37517035 | 2023 | Biallelic MED27 variants lead to variable ponto-cerebello-lental degeneration with movement disorders. | 0 |
| 36371844 | 2022 | Knockdown of mediator complex subunit 27 suppresses gastric cancer cell metastasis and angiogenesis via Wnt/β-catenin pathway. | 3 |
| 36371844 | 2022 | Knockdown of mediator complex subunit 27 suppresses gastric cancer cell metastasis and angiogenesis via Wnt/β-catenin pathway. | 3 |
| 33162555 | 2021 | CRSP8 promotes thyroid cancer progression by antagonizing IKKα-induced cell differentiation. | 7 |
| 33443317 | 2021 | MED27 Variants Cause Developmental Delay, Dystonia, and Cerebellar Hypoplasia. | 11 |
| 33162555 | 2021 | CRSP8 promotes thyroid cancer progression by antagonizing IKKα-induced cell differentiation. | 7 |
| 33443317 | 2021 | MED27 Variants Cause Developmental Delay, Dystonia, and Cerebellar Hypoplasia. | 11 |
| 32633372 | 2020 | MED27 promotes malignant behavior of cells by affecting Sp1 in breast cancer. | 3 |
| 32633372 | 2020 | MED27 promotes malignant behavior of cells by affecting Sp1 in breast cancer. | 3 |
| 29693135 | 2018 | MicroRNA-18a inhibits cell growth and induces apoptosis in osteosarcoma by targeting MED27. | 12 |
| 29730647 | 2018 | Silencing of MED27 inhibits adrenal cortical carcinogenesis by targeting the Wnt/β-catenin signaling pathway and the epithelial-mesenchymal transition process. | 5 |
| 29693135 | 2018 | MicroRNA-18a inhibits cell growth and induces apoptosis in osteosarcoma by targeting MED27. | 12 |
Citation
Dessen P
MED27 (mediator complex subunit 27)
Atlas Genet Cytogenet Oncol Haematol. 2016-08-01
Online version: http://atlasgeneticsoncology.org/gene/55849/med27-(mediator-complex-subunit-27)
