ITM2A (integral membrane protein 2A)

2016-08-01  

Identity

HGNC
ITM2A
LOCATION
Xq21.1
LOCUSID
9452
ALIAS
BRICD2A,E25A
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 9452
MIM: 300222
HGNC: 6173
Ensembl: ENSG00000078596

Variants:

dbSNP: 9452
ClinVar: 9452
TCGA: ENSG00000078596
COSMIC: ITM2A

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000078596ENST00000373298O43736
ENSG00000078596ENST00000434584O43736

Expression (GTEx)

0
50
100
150
200
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

References

Pubmed IDYearTitleCitations
367654702023[Study on the Relationship between Integrin 2A and Drug Resistance in Chronic Myeloid Leukemia].0
369882462023Association of ITM2A rs1751094 polymorphism on X chromosome in Korean pediatric patients with autoimmune thyroid disease.1
367654702023[Study on the Relationship between Integrin 2A and Drug Resistance in Chronic Myeloid Leukemia].0
369882462023Association of ITM2A rs1751094 polymorphism on X chromosome in Korean pediatric patients with autoimmune thyroid disease.1
341619512021Downregulation of ITM2A Gene Expression in Macrophages of Patients with Ankylosing Spondylitis.2
344407722021Integral Membrane Protein 2A Is a Negative Regulator of Canonical and Non-Canonical Hedgehog Signalling.1
341619512021Downregulation of ITM2A Gene Expression in Macrophages of Patients with Ankylosing Spondylitis.2
344407722021Integral Membrane Protein 2A Is a Negative Regulator of Canonical and Non-Canonical Hedgehog Signalling.1
327270902020GPR174 and ITM2A Gene Polymorphisms rs3827440 and rs5912838 on the X chromosome in Korean Children with Autoimmune Thyroid Disease.6
327270902020GPR174 and ITM2A Gene Polymorphisms rs3827440 and rs5912838 on the X chromosome in Korean Children with Autoimmune Thyroid Disease.6
314389692019Integral membrane protein 2A inhibits cell growth in human breast cancer via enhancing autophagy induction.18
314389692019Integral membrane protein 2A inhibits cell growth in human breast cancer via enhancing autophagy induction.18
278096952017ITM2A Expands Evidence for Genetic and Environmental Interaction in Graves Disease Pathogenesis.10
278096952017ITM2A Expands Evidence for Genetic and Environmental Interaction in Graves Disease Pathogenesis.10
266912192016Loss of ITM2A, a novel tumor suppressor of ovarian cancer through G2/M cell cycle arrest, is a poor prognostic factor of epithelial ovarian cancer.18

Citation

Dessen P

ITM2A (integral membrane protein 2A)

Atlas Genet Cytogenet Oncol Haematol. 2016-08-01

Online version: http://atlasgeneticsoncology.org/gene/55872/itm2a-(integral-membrane-protein-2a)