SLC14A2 (solute carrier family 14 member 2)

2016-08-01  

Identity

HGNC
SLC14A2
LOCATION
18q12.3
LOCUSID
8170
ALIAS
HUT2,UT-A2,UT2,UTA,UTR,hUT-A6
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 8170
MIM: 601611
HGNC: 10919
Ensembl: ENSG00000132874

Variants:

dbSNP: 8170
ClinVar: 8170
TCGA: ENSG00000132874
COSMIC: SLC14A2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000132874ENST00000255226Q15849
ENSG00000132874ENST00000323329E7EPU1
ENSG00000132874ENST00000586448Q15849

Expression (GTEx)

0
1
2
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Pathways

PathwaySourceExternal ID
Transmembrane transport of small moleculesREACTOMER-HSA-382551
SLC-mediated transmembrane transportREACTOMER-HSA-425407
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compoundsREACTOMER-HSA-425366

PharmGKB

Entity IDNameTypeEvidenceAssociationPKPDPMIDs
PA444552HypertensionDiseaseClinicalAnnotationassociatedPD17344938
PA450631nifedipineChemicalClinicalAnnotationassociatedPD17344938

References

Pubmed IDYearTitleCitations
292798522017The Expression of AQP5 and UTs in the Sweat Glands of Uremic Patients.0
292798522017The Expression of AQP5 and UTs in the Sweat Glands of Uremic Patients.0
269276692016Endogenous transmembrane protein UT2 inhibits pSTAT3 and suppresses hematological malignancy.7
269276692016Endogenous transmembrane protein UT2 inhibits pSTAT3 and suppresses hematological malignancy.7
252983382014Genes and proteins of urea transporters.12
252983402014Expression of urea transporters and their regulation.5
252983412014Biochemical properties of urea transporters.3
252983382014Genes and proteins of urea transporters.12
252983402014Expression of urea transporters and their regulation.5
252983412014Biochemical properties of urea transporters.3
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
207973942010Genetic variants of human urea transporter-2 are associated with metabolic syndrome in Asian population.6
207973942010Genetic variants of human urea transporter-2 are associated with metabolic syndrome in Asian population.6
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.78
207973942010Genetic variants of human urea transporter-2 are associated with metabolic syndrome in Asian population.6

Citation

Dessen P

SLC14A2 (solute carrier family 14 member 2)

Atlas Genet Cytogenet Oncol Haematol. 2016-08-01

Online version: http://atlasgeneticsoncology.org/gene/55875/slc14a2-(solute-carrier-family-14-member-2)