Identity
HGNC
LOCATION
19q13.2
LOCUSID
ALIAS
BVRB,FLR,HEL-S-10,SDR43U1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 645
MIM: 600941
HGNC: 1063
Ensembl: ENSG00000090013
Variants:
dbSNP: 645
ClinVar: 645
TCGA: ENSG00000090013
COSMIC: BLVRB
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA450457 | methylene blue | Chemical | LabelAnnotation, Pathway | associated | 23913015 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37371462 | 2023 | Biliverdin Reductase B Is a Plasma Biomarker for Intraplaque Hemorrhage and a Predictor of Ischemic Stroke in Patients with Symptomatic Carotid Atherosclerosis. | 0 |
| 37371462 | 2023 | Biliverdin Reductase B Is a Plasma Biomarker for Intraplaque Hemorrhage and a Predictor of Ischemic Stroke in Patients with Symptomatic Carotid Atherosclerosis. | 0 |
| 32246827 | 2020 | Structure, dynamics and function of the evolutionarily changing biliverdin reductase B family. | 9 |
| 32246827 | 2020 | Structure, dynamics and function of the evolutionarily changing biliverdin reductase B family. | 9 |
| 29487133 | 2018 | In silico and crystallographic studies identify key structural features of biliverdin IXβ reductase inhibitors having nanomolar potency. | 4 |
| 29500232 | 2018 | Heme degradation enzyme biliverdin IXβ reductase is required for stem cell glutamine metabolism. | 7 |
| 29487133 | 2018 | In silico and crystallographic studies identify key structural features of biliverdin IXβ reductase inhibitors having nanomolar potency. | 4 |
| 29500232 | 2018 | Heme degradation enzyme biliverdin IXβ reductase is required for stem cell glutamine metabolism. | 7 |
| 26708147 | 2016 | MicroRNA-127-5p targets the biliverdin reductase B/nuclear factor-κB pathway to suppress cell growth in hepatocellular carcinoma cells. | 34 |
| 27207795 | 2016 | BLVRB redox mutation defines heme degradation in a metabolic pathway of enhanced thrombopoiesis in humans. | 18 |
| 26708147 | 2016 | MicroRNA-127-5p targets the biliverdin reductase B/nuclear factor-κB pathway to suppress cell growth in hepatocellular carcinoma cells. | 34 |
| 27207795 | 2016 | BLVRB redox mutation defines heme degradation in a metabolic pathway of enhanced thrombopoiesis in humans. | 18 |
| 25726384 | 2015 | Biliverdin reductase isozymes in metabolism. | 70 |
| 25726384 | 2015 | Biliverdin reductase isozymes in metabolism. | 70 |
| 18241201 | 2008 | Computational and experimental studies on the catalytic mechanism of biliverdin-IXbeta reductase. | 14 |
Citation
Dessen P
BLVRB (biliverdin reductase B)
Atlas Genet Cytogenet Oncol Haematol. 2016-08-01
Online version: http://atlasgeneticsoncology.org/gene/55876/blvrb-(biliverdin-reductase-b)
