TMPRSS11D (transmembrane serine protease 11D)

2016-08-01  

Identity

HGNC
TMPRSS11D
LOCATION
4q13.2
LOCUSID
9407
ALIAS
ASP,HAT
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 9407
MIM: 605369
HGNC: 24059
Ensembl: ENSG00000153802

Variants:

dbSNP: 9407
ClinVar: 9407
TCGA: ENSG00000153802
COSMIC: TMPRSS11D

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000153802ENST00000283916O60235
ENSG00000153802ENST00000514868H0Y8K7

Expression (GTEx)

0
50
100
150
200
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
365295622023HαT is associated with increased risk for severe Hymenoptera venom-triggered anaphylaxis.2
376660682023TMPRSS11D/ALR-mediated ER stress regulates the function of myeloid-derived suppressor cells in the cervical cancer microenvironment.1
365295622023HαT is associated with increased risk for severe Hymenoptera venom-triggered anaphylaxis.2
376660682023TMPRSS11D/ALR-mediated ER stress regulates the function of myeloid-derived suppressor cells in the cervical cancer microenvironment.1
336710762021TMPRSS11D and TMPRSS13 Activate the SARS-CoV-2 Spike Protein.42
336710762021TMPRSS11D and TMPRSS13 Activate the SARS-CoV-2 Spike Protein.42
306774062019Human airway trypsin-like protease enhances interleukin-8 synthesis in bronchial epithelial cells by activating protease-activated receptor 2.6
306774062019Human airway trypsin-like protease enhances interleukin-8 synthesis in bronchial epithelial cells by activating protease-activated receptor 2.6
291228472018Human airway trypsin-like protease exerts potent, antifibrotic action in pulmonary fibrosis.3
302828702018Human airway trypsin-like protease (HAT) is released into saliva.1
306479112018Functional proteomic profiling reveals KLK13 and TMPRSS11D as active proteases in the lower female reproductive tract.2
291228472018Human airway trypsin-like protease exerts potent, antifibrotic action in pulmonary fibrosis.3
302828702018Human airway trypsin-like protease (HAT) is released into saliva.1
306479112018Functional proteomic profiling reveals KLK13 and TMPRSS11D as active proteases in the lower female reproductive tract.2
280862122017High TMPRSS11D protein expression predicts poor overall survival in non-small cell lung cancer.6

Citation

Dessen P

TMPRSS11D (transmembrane serine protease 11D)

Atlas Genet Cytogenet Oncol Haematol. 2016-08-01

Online version: http://atlasgeneticsoncology.org/gene/55889/tmprss11d-(transmembrane-serine-protease-11d)