Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 54209
MIM: 605086
HGNC: 17761
Ensembl: ENSG00000095970
Variants:
dbSNP: 54209
ClinVar: 54209
TCGA: ENSG00000095970
COSMIC: TREM2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000095970 | ENST00000338469 | Q9NZC2 |
| ENSG00000095970 | ENST00000373113 | Q9NZC2 |
| ENSG00000095970 | ENST00000373113 | Q5TCX1 |
| ENSG00000095970 | ENST00000373122 | Q9NZC2 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36403150 | 2024 | TREM-2: friend or foe in infectious diseases? | 2 |
| 37498431 | 2024 | TREM-2 Drives Development of Multiple Sclerosis by Promoting Pathogenic Th17 Polarization. | 0 |
| 37740498 | 2024 | Soluble TREM2 triggers microglial dysfunction in neuromyelitis optica spectrum disorders. | 3 |
| 37941134 | 2024 | TREM2 mediates MHCII-associated CD4+ T-cell response against gliomas. | 3 |
| 38012119 | 2024 | Effect of triggering receptor expressed on myeloid cells 2-associated alterations on lipid metabolism in macrophages in the development of non-alcoholic fatty liver disease. | 0 |
| 38237157 | 2024 | Triggering receptor expressed on myeloid cells 2 (TREM2) regulates phagocytosis in glioblastoma. | 4 |
| 38244651 | 2024 | TREM2 in Alzheimer's disease: Structure, function, therapeutic prospects, and activation challenges. | 0 |
| 38326398 | 2024 | TREM2 mediates phagocytosis in glioblastoma. | 0 |
| 38505612 | 2024 | Dynamic pathological analysis reveals a protective role against skin fibrosis for TREM2-dependent macrophages. | 0 |
| 38592304 | 2024 | Different Splice Isoforms of Peripheral Triggering Receptor Expressed on Myeloid Cells 2 mRNA Expressions are Associated With Cognitive Decline in Mild Dementia Due to Alzheimer's Disease and Reflect Central Neuroinflammation. | 0 |
| 38609037 | 2024 | Myeloid Trem2 ameliorates the progression of metabolic dysfunction-associated steatotic liver disease by regulating macrophage pyroptosis and inflammation resolution. | 0 |
| 38613944 | 2024 | SHIP inhibition mediates select TREM2-induced microglial functions. | 0 |
| 36403150 | 2024 | TREM-2: friend or foe in infectious diseases? | 2 |
| 37498431 | 2024 | TREM-2 Drives Development of Multiple Sclerosis by Promoting Pathogenic Th17 Polarization. | 0 |
| 37740498 | 2024 | Soluble TREM2 triggers microglial dysfunction in neuromyelitis optica spectrum disorders. | 3 |
Citation
Dessen P
TREM2 (triggering receptor expressed on myeloid cells 2)
Atlas Genet Cytogenet Oncol Haematol. 2016-08-01
Online version: http://atlasgeneticsoncology.org/gene/55900/trem2-(triggering-receptor-expressed-on-myeloid-cells-2)
