Identity
HGNC
LOCATION
1q23.3
LOCUSID
ALIAS
19A,CD319,CRACC,CS1
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 57823
MIM: 606625
HGNC: 21394
Ensembl: ENSG00000026751
Variants:
dbSNP: 57823
ClinVar: 57823
TCGA: ENSG00000026751
COSMIC: SLAMF7
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Immune System | REACTOME | R-HSA-168256 |
| Adaptive Immune System | REACTOME | R-HSA-1280218 |
| Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell | REACTOME | R-HSA-198933 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37420084 | 2023 | Identification and elucidation of cross talk between SLAM Family Member 7 (SLAMF7) and Toll-like receptor (TLR) pathways in monocytes and macrophages. | 1 |
| 37754488 | 2023 | SLAMF7 as a Promising Immunotherapeutic Target in Multiple Myeloma Treatments. | 2 |
| 37420084 | 2023 | Identification and elucidation of cross talk between SLAM Family Member 7 (SLAMF7) and Toll-like receptor (TLR) pathways in monocytes and macrophages. | 1 |
| 37754488 | 2023 | SLAMF7 as a Promising Immunotherapeutic Target in Multiple Myeloma Treatments. | 2 |
| 34693521 | 2022 | SLAMF7 selectively favors degranulation to promote cytotoxicity in human NK cells. | 5 |
| 35148199 | 2022 | SLAMF7 engagement superactivates macrophages in acute and chronic inflammation. | 22 |
| 36199066 | 2022 | SLAMF7 modulates B cells and adaptive immunity to regulate susceptibility to CNS autoimmunity. | 4 |
| 34693521 | 2022 | SLAMF7 selectively favors degranulation to promote cytotoxicity in human NK cells. | 5 |
| 35148199 | 2022 | SLAMF7 engagement superactivates macrophages in acute and chronic inflammation. | 22 |
| 36199066 | 2022 | SLAMF7 modulates B cells and adaptive immunity to regulate susceptibility to CNS autoimmunity. | 4 |
| 33017079 | 2021 | CD319 (SLAMF7) an alternative marker for detecting plasma cells in the presence of daratumumab or elotuzumab. | 12 |
| 33288545 | 2021 | SLAMF7 Signaling Reprograms T Cells toward Exhaustion in the Tumor Microenvironment. | 35 |
| 33420283 | 2021 | Combinatorial targeting of multiple myeloma by complementing T cell engaging antibody fragments. | 6 |
| 34732412 | 2021 | SLAMF7 and TREM1 Mediate Immunogenic Cell Death in Colorectal Cancer Cells: Focus on Microsatellite Stability. | 4 |
| 33017079 | 2021 | CD319 (SLAMF7) an alternative marker for detecting plasma cells in the presence of daratumumab or elotuzumab. | 12 |
Citation
Dessen P
SLAMF7 (SLAM family member 7)
Atlas Genet Cytogenet Oncol Haematol. 2016-08-01
Online version: http://atlasgeneticsoncology.org/gene/55902/gene-explorer/case-report-explorer/
