TMPRSS11E (transmembrane serine protease 11E)

2016-08-01  

Identity

HGNC
TMPRSS11E
LOCATION
4q13.2
LOCUSID
28983
ALIAS
DESC1,TMPRSS11E2
FUSION GENES
Show Gene Fusions

Other Information

Locus ID:

NCBI: 28983
MIM: 610399
HGNC: 24465
Ensembl: ENSG00000087128

Variants:

dbSNP: 28983
ClinVar: 28983
TCGA: ENSG00000087128
COSMIC: TMPRSS11E

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000087128ENST00000305363Q9UL52
ENSG00000087128ENST00000510647H0Y9G7

Expression (GTEx)

0
50
100
150
200
250
300
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
359516702022Elevated expression of the membrane-anchored serine protease TMPRSS11E in NSCLC progression.0
359516702022Elevated expression of the membrane-anchored serine protease TMPRSS11E in NSCLC progression.0
268563902016DESC1, a novel tumor suppressor, sensitizes cells to apoptosis by downregulating the EGFR/AKT pathway in esophageal squamous cell carcinoma.15
268563902016DESC1, a novel tumor suppressor, sensitizes cells to apoptosis by downregulating the EGFR/AKT pathway in esophageal squamous cell carcinoma.15
251228022014DESC1 and MSPL activate influenza A viruses and emerging coronaviruses for host cell entry.54
251228022014DESC1 and MSPL activate influenza A viruses and emerging coronaviruses for host cell entry.54
173888112007Crystal structure of the catalytic domain of DESC1, a new member of the type II transmembrane serine proteinase family.23
173888112007Crystal structure of the catalytic domain of DESC1, a new member of the type II transmembrane serine proteinase family.23

Citation

Dessen P

TMPRSS11E (transmembrane serine protease 11E)

Atlas Genet Cytogenet Oncol Haematol. 2016-08-01

Online version: http://atlasgeneticsoncology.org/gene/55905/tmprss11e-(transmembrane-serine-protease-11e)