Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 63826
MIM: 606477
HGNC: 14398
Ensembl: ENSG00000167720
Variants:
dbSNP: 63826
ClinVar: 63826
TCGA: ENSG00000167720
COSMIC: SRR
RNA/Proteins
Expression (GTEx)
Pathways
| Pathway | Source | External ID |
|---|---|---|
| Glycine, serine and threonine metabolism | KEGG | ko00260 |
| Glycine, serine and threonine metabolism | KEGG | hsa00260 |
| Metabolic pathways | KEGG | hsa01100 |
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37523600 | 2023 | The Prognostic Role of Serine Racemase in Patients With Pancreatic Cancer: A New Marker in Cancer Metabolism. | 1 |
| 37523600 | 2023 | The Prognostic Role of Serine Racemase in Patients With Pancreatic Cancer: A New Marker in Cancer Metabolism. | 1 |
| 32971286 | 2021 | Human serine racemase is inhibited by glyceraldehyde 3-phosphate, but not by glyceraldehyde 3-phosphate dehydrogenase. | 2 |
| 33249721 | 2021 | The allosteric interplay between S-nitrosylation and glycine binding controls the activity of human serine racemase. | 8 |
| 35046895 | 2021 | qPCR Analysis Reveals Association of Differential Expression of SRR, NFKB1, and PDE4B Genes With Type 2 Diabetes Mellitus. | 2 |
| 32971286 | 2021 | Human serine racemase is inhibited by glyceraldehyde 3-phosphate, but not by glyceraldehyde 3-phosphate dehydrogenase. | 2 |
| 33249721 | 2021 | The allosteric interplay between S-nitrosylation and glycine binding controls the activity of human serine racemase. | 8 |
| 35046895 | 2021 | qPCR Analysis Reveals Association of Differential Expression of SRR, NFKB1, and PDE4B Genes With Type 2 Diabetes Mellitus. | 2 |
| 31621607 | 2019 | Impaired serine metabolism complements LRRK2-G2019S pathogenicity in PD patients. | 9 |
| 31621607 | 2019 | Impaired serine metabolism complements LRRK2-G2019S pathogenicity in PD patients. | 9 |
| 29025687 | 2018 | Serine Racemase and D-serine in the Amygdala Are Dynamically Involved in Fear Learning. | 22 |
| 29338921 | 2018 | Faster progression from MCI to probable AD for carriers of a single-nucleotide polymorphism associated with type 2 diabetes. | 12 |
| 29363864 | 2018 | SRR intronic variation inhibits expression of its neighbouring SMG6 gene and protects against temporal lobe epilepsy. | 3 |
| 29566294 | 2018 | Inflammatory cytokine-mediated induction of serine racemase in atopic dermatitis. | 2 |
| 29899358 | 2018 | Glutamine 89 is a key residue in the allosteric modulation of human serine racemase activity by ATP. | 11 |
Citation
Dessen P
SRR (serine racemase)
Atlas Genet Cytogenet Oncol Haematol. 2016-08-01
Online version: http://atlasgeneticsoncology.org/gene/55906/
