Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 157848
MIM: 610772
HGNC: 26328
Ensembl: ENSG00000165066
Variants:
dbSNP: 157848
ClinVar: 157848
TCGA: ENSG00000165066
COSMIC: NKX6-3
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000165066 | ENST00000518699 | A6NJ46 |
| ENSG00000165066 | ENST00000524115 | A6NJ46 |
Expression (GTEx)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 30686901 | 2019 | NKX6.3 protects against gastric mucosal atrophy by downregulating β-amyloid production. | 2 |
| 30710084 | 2019 | Genome-wide gene-based analyses of weight loss interventions identify a potential role for NKX6.3 in metabolism. | 7 |
| 30686901 | 2019 | NKX6.3 protects against gastric mucosal atrophy by downregulating β-amyloid production. | 2 |
| 30710084 | 2019 | Genome-wide gene-based analyses of weight loss interventions identify a potential role for NKX6.3 in metabolism. | 7 |
| 30514953 | 2018 | Multiple genetic mutations caused by NKX6.3 depletion contribute to gastric tumorigenesis. | 4 |
| 30514953 | 2018 | Multiple genetic mutations caused by NKX6.3 depletion contribute to gastric tumorigenesis. | 4 |
| 28584243 | 2017 | NKX6.3 Regulates Reactive Oxygen Species Production by Suppressing NF-kB and DNMT1 Activities in Gastric Epithelial Cells. | 4 |
| 28584243 | 2017 | NKX6.3 Regulates Reactive Oxygen Species Production by Suppressing NF-kB and DNMT1 Activities in Gastric Epithelial Cells. | 4 |
| 26743476 | 2016 | Inactivation of NKX6.3 in the stomach leads to abnormal expression of CDX2 and SOX2 required for gastric-to-intestinal transdifferentiation. | 8 |
| 27333045 | 2016 | NKX6.3 Is a Transcription Factor for Wnt/β-catenin and Rho-GTPase Signaling-Related Genes to Suppress Gastric Cancer Progression. | 9 |
| 26743476 | 2016 | Inactivation of NKX6.3 in the stomach leads to abnormal expression of CDX2 and SOX2 required for gastric-to-intestinal transdifferentiation. | 8 |
| 27333045 | 2016 | NKX6.3 Is a Transcription Factor for Wnt/β-catenin and Rho-GTPase Signaling-Related Genes to Suppress Gastric Cancer Progression. | 9 |
| 26314965 | 2015 | NKX6.3 controls gastric differentiation and tumorigenesis. | 9 |
| 26314965 | 2015 | NKX6.3 controls gastric differentiation and tumorigenesis. | 9 |
Citation
Dessen P
NKX6-3 (NK6 homeobox 3)
Atlas Genet Cytogenet Oncol Haematol. 2016-08-01
Online version: http://atlasgeneticsoncology.org/gene/55907/nkx6-3-(nk6-homeobox-3)
